Chemistry:Monosodium citrate
From HandWiki
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| Names | |
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| IUPAC name
Sodium 2-(carboxymethyl)-2,4-dihydroxy-4-oxobutanoate[1]
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| Other names
sodium dihydrogen 2-hydroxypropane-1,2,3-tricarboxylate
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| Identifiers | |
3D model (JSmol)
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| Properties | |
| C6H7NaO7 | |
| Molar mass | 214.105 g·mol−1 |
| Appearance | white powder hygroscopic |
| Odor | odorless |
| Melting point | 212 °C (414 °F; 485 K) |
| Boiling point | 309.6 °C (589.3 °F; 582.8 K) |
| soluble | |
| Solubility | negligible in ethanol |
| Acidity (pKa) | 3.50–3.80 |
| Structure[2] | |
| Monoclinic | |
| P21/a (No. 4) | |
Formula units (Z)
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4 |
| Hazards | |
| Safety data sheet | Carl Roth |
| Lethal dose or concentration (LD, LC): | |
LD50 (median dose)
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5400 mg/kg (mouse, oral) >2000 mg/kg (rat, dermal) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
 verify (what is   ?)
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| Infobox references | |
Monosodium citrate, more correctly, sodium dihydrogen citrate (Latin: natrium citricum acidulatum), is an acid salt of citric acid. Disodium citrate and trisodium citrate are also known. It can be prepared by partial neutralisation of citric acid[3] with an aqueous solution of sodium bicarbonate or carbonate. It has a slightly acidic taste.[3]
- NaHCO3 + C6H8O7 → NaC6H7O7 + CO2 + H2O
- Na2CO3 + 2C6H8O7 → 2NaC6H7O7 + CO2 + H2O
It is highly soluble in water and practically insoluble in ethanol.[3] Monosodium citrate is used as an anticoagulant in blood samples.[4] It is used as an alkalinizing agent to prevent kidney stone disease.[5] The crystals form as nearly perfect cubes.[6]
References
- ↑ "Sodium dihydrogen citrate". https://pubchem.ncbi.nlm.nih.gov/compound/23662352#section=IUPAC-Name&fullscreen=true.
- ↑ Glusker, Jenny P.; van der Helm, D.; Love, Warner E.; Dornberg, Marilyn L.; Patterson, A. L. (June 1960). "The State of Ionization of Crystalline Sodium Dihydrogen Citrate1" (in en). Journal of the American Chemical Society 82 (11): 2964–2965. doi:10.1021/ja01496a071. ISSN 0002-7863. Bibcode: 1960JAChS..82.2964G. https://pubs.acs.org/doi/10.1021/ja01496a071. Retrieved 22 July 2022.
- ↑ 3.0 3.1 3.2 "Monosodium Citrate - Jungbunzlauer". https://www.jungbunzlauer.com/en/products/special-salts/monosodium-citrate.html.
- ↑ Clinical Hematology: Theory and Procedures, Mary Louise Turgeon
- ↑ PubChem. "Monosodium citrate" (in en). https://pubchem.ncbi.nlm.nih.gov/compound/23666341.
- ↑ Hitchcock, David I. (March 1946). "Sodium Hydrogen Citrates" (in en). Journal of the American Chemical Society 68 (3): 524–525. doi:10.1021/ja01207a507. ISSN 0002-7863. PMID 21015754. Bibcode: 1946JAChS..68R.524H. https://pubs.acs.org/doi/10.1021/ja01207a507. Retrieved 22 July 2022.
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