Medicine:Autologous cultured chondrocytes on porcine collagen membrane
| Autologous cultured chondrocytes on porcine collagen membrane | |
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| Other names | MACI |
| Specialty | orthopedic |
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| Trade names | Maci |
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Autologous cultured chondrocytes on porcine collagen membrane (Maci) is a treatment to correct cartilage defects in the knee.[1] It is used to treat symptomatic, full-thickness cartilage defects of the knee with or without bone involvement.[2][1] Autologous cultured chondrocytes on porcine collagen membrane is an autologous cellularized scaffold product.[1] This treatment is approved by the US Food and Drug Administration (FDA).[1] It is only administered to adults.[1] Healthy cartilage is removed from the person's own knees and a 'scaffold' is created on which the healthy tissue growths.[1] This is an autologous matrix-induced chondrogenesis procedure which prevents tissue rejection complications since the transplanted cartilage comes from the same person.[3]
Autologous cultured chondrocytes on porcine collagen membrane was approved for use in the United States in May 2019.[2]
See also
- Microfracturing
- Knee osteoarthritis
- Knee pain
References
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 "Maci- autologous cultured chondrocytes implant". 23 October 2019. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=0c336c02-8c4c-4aa8-a992-9d2890a2539c.
- ↑ 2.0 2.1 2.2 "Maci (Autologous Cultured Chondrocytes on a Porcine Collagen Membrane)". https://www.fda.gov/vaccines-blood-biologics/cellular-gene-therapy-products/maci-autologous-cultured-chondrocytes-porcine-collagen-membrane. Retrieved 13 May 2017.
This article incorporates text from this source, which is in the public domain.
- ↑ "FDA Clears Novel Scaffold for Knee Cartilage Repair". Medscape. December 14, 2016. https://www.medscape.com/viewarticle/873294.
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