Medicine:Cancer survivor

From HandWiki
Short description: Person with cancer who is still alive
Life-size metal statues of people look like they have just joyfully emerged from a series of abstract door frames representing cancer as a journey
Sculpture in a park with a theme of cancer survivorship


A cancer survivor is a person with cancer of any type who is still living. Whether a person becomes a survivor at the time of diagnosis or after completing treatment, whether people who are actively dying are considered survivors, and whether healthy friends and family members of the cancer patient are also considered survivors, varies from group to group. Some people who have been diagnosed with cancer reject the term survivor or disagree with some definitions of it.

How many people are cancer survivors depends on the definition used. Nearly 65% of adults diagnosed with cancer in the developed world are expected to live at least five years after the cancer is discovered.[1] In the U.S. for example, about 11 million Americans alive today—one in 30 people–are either currently undergoing treatment for cancer or have done so in the past.[2]

Many cancer survivors describe the process of living with and beating cancer as a life-changing experience.[3] It is not uncommon for survivors to use the experience as opportunities for creative self-transformation into a "better person" or as motivation to meet goals of great personal importance, such as climbing a mountain or reconciling with an estranged family member. This process of posttraumatic growth is called benefit finding.[4] Cancer survivors often have specific medical and non-medical needs related to their cancer experience.

Definitions and alternatives

Macmillan Cancer Support in the UK defines a cancer survivor as someone who is "living with or beyond cancer", namely someone who:

  • has completed initial cancer management and has no apparent evidence of active disease;
  • is living with progressive disease and may be receiving cancer treatment, but is not in the terminal phases of illness;
  • or has had cancer in the past.[5]

The National Coalition for Cancer Survivorship (NCCS) pioneered the definition of survivor as being any person diagnosed with cancer, from the time of initial diagnosis until his or her death. This definition of "survivor" includes people who are dying from untreatable cancer. NCCS later expanded the definition of survivor even further to include family, friends and voluntary caregivers who are "impacted by the survivorship experience" in any way.[6] The US National Cancer Institute's Office of Cancer Survivorship uses a variant of this expanded definition.[7]

The word survivor is a loaded term.[3] Within the breast cancer culture, survivorship is conferred upon women and men who are perceived as having had emotional or physical trauma, even if their breast cancer was a non-life-threatening pre-cancerous condition like LCIS or DCIS. The term tends to erase and degrade people who are dying of incurable cancer. This idea of survivorship emphasizes and values longevity of life after diagnosis, while overlooking issues of quality of life.[3]

Some people reject the term survivor as being a narrow conceptualization of highly variable human experiences. Alternatives include alivers and thrivers, which put emphasis on living as well as possible, despite limitations and disability.[3] A third term, the diers, is used by some terminally ill patients who reject the claim that dying is part of survivorship or should be covered up with inappropriately optimistic language.[3]

The term previvor has been used to describe unaffected carriers. Unaffected carriers, or previvors, are those who have not been diagnosed with cancer, but who know that they are likely to develop cancer due to certain genetic mutations that form a known cancer syndrome. They have survived the predisposition, or higher risk, of cancer.[8][9] As such, this is the first generation in human history who, armed with information about a predisposition to a cancer after opting into DNA testing, can make informed choices prior to cancer diagnosis. The typical previvor has tested positive for a BRCA mutation, learned that she is at high risk for developing breast cancer and ovarian cancer, and is attempting to manage that risk through a combination of increased surveillance through mammograms, breast MRIs, pelvic ultrasounds, oophorectomy, bilateral mastectomy, and other medical procedures. There has been much controversy over the term previvor, due to the fact that the name compares these healthy women to people who have already been diagnosed with cancer.

Needs of cancer survivors

People who have finished cancer treatment often have psychological and physical medical challenges.[10] These effects can vary from person to person, change over time, and range in intensity from mild and intermittent to fully disabling. They commonly include fatigue,[11] pain,[11] sleep problems,[12] physical side effects like lymphoedema,[13] weight gain,[14] anxiety and depression,[15] fear of cancer recurrence,[16] and impaired quality of life.[17]

Psychosocial

Returning to life

If the treatment is lengthy and disruptive, many patients experience some difficulty in returning to normal daily life.[18] The energy needed to cope with a rigorous treatment program may have caused them to disconnect from previous daily patterns, such as working, normal self-care, and housekeeping. Some survivors become dependent on the attention and sympathy that they received during their treatment and feel neglected when life returns to normal.[19][20] There are tremendous implications that cancer has on the relationships that survivors have with their loved ones (particularly their partners) once their cancer has been treated,[21] and social support plays a critical role in their long-term emotional adjustment.[22]

Cancer survivors tend to be more resilient than the general population.[23]

Ongoing effects

Some survivors have to adjust to the idea that they will never be cured.

Some survivors, even if the cancer has been permanently cured, struggle emotionally from the trauma of having experienced a life-threatening disease.[24] Cancer survivors experience more psychological distress than those who have never had cancer (5.6% compared to 3.0%)[25] Serious psychological distress was seen 40% more among cancer survivors of five years or more than in those who have never had cancer.[25] About 10% develop major depressive disorder; others experience an adjustment disorder.[24] In young adult cancer survivors, one small study found that 20% of participants met the full clinical diagnosis of post-traumatic stress disorder (PTSD), and 45% to 95% displayed at least one symptom of PTSD.[26] Survivors of adult cancer are at an increased risk of suicidal ideation (having thoughts about suicide),[27] while as many as 13% of childhood cancer survivors experience suicidal ideation.[28] Issues of pain and physical ailments have been hypothesized as major contributing factors in cancer survivors experiencing this suicidal ideation.

Fear of cancer recurrence

Patients whose cancer is in remission may still have to cope with the uncertainty that at any time their cancer could return without warning. After the initial treatment has ended, anxiety is more common among cancer survivors than among other people.[29] This anxiety regarding the cancer's return is referred to as fear of cancer recurrence.[30] Many patients are anxious that any minor symptom indicates that the cancer has returned, with as many as 9 in 10 patients fearful that their cancer will recur or spread.[2] In addition to the appearance of any new aches and pains, common triggers for a fear that the cancer may return include hearing that someone else has been diagnosed with cancer, annual medical exams to determine whether the cancer recurred, and news stories about cancer.[31] This anxiety leads to more medical check ups, which can be measured even after a period of up to ten years.[32] This fear can have a significant effect on individuals' lives, resulting in difficulties in their daily life such as work and socialising, and difficulties planning for the future.[33] Overall, fear of cancer recurrence is related to a reduced quality of life in cancer survivors.[33]

While Fear of Cancer Recurrence (FCR) can be adaptive at low levels, high levels of FCR require psychological treatment. At present, there are no psychometrically sound measures of FCR, which makes research into the effectiveness of treatment protocols difficult to interpret.[34] Treatments that are being investigated include: cognitive-behavioural therapy,[35] meta-cognitive therapy,[36] cognitive-existential group therapy,[37] mindfulness-based interventions,[38] and physical exercise.[39]

Survivorship

The cultural ideal of a survivor may add to individual patients' distress if the patient is unable or unwilling to live up to the ideal.[3] As described by Gayle Sulik in her book Pink Ribbon Blues: How Breast Cancer Culture Undermines Women's Health, the ideal survivor is bravely committed to mainstream medicine and optimistic or even certain of a physical cure. She[Notes 1] is open about diagnosis and treatment and become an educated, empowered medical consumer. The ideal survivor, like a superwoman who simultaneously manages her home, family, and career, struggles valiantly to prevent cancer from affecting loved ones by appearing, behaving, and working as much as possible. Once the immediate crisis is past, the person may feel strongly pressured to donate time, money, and energy to cancer-related organizations. Above all, the ideal survivor does not die of cancer. People who publicly conform to this ideal are given social status and respect.[3]

Physical

In terms of medical challenges, some survivors experience cancer-related fatigue, may have long-term side effects from cancer and its treatment, and may need extensive rehabilitation for mobility and function if aggressive surgery was required to remove the cancer. They may experience temporary or persistent post-chemotherapy cognitive impairment. Some young survivors lose their ability to have children.

Cancer survivors frequently need medical monitoring, and some treatments for unrelated diseases in the future may be contraindicated. For example, a patient who has had a significant amount of radiation therapy may not be a good candidate for more radiation treatments in the future. To assist with these needs, "survivor care plans" have been promoted. These are personalized documents that describe the person's diagnosis and treatment in detail, list common known side effects, and specifically outline the steps that the survivor should take in the future, ranging from maintaining a healthy weight to receiving specific medical tests on a stated schedule.[40]

Medical tests to determine whether the cancer has returned commonly provoke fears. Informally, this is called scanxiety, a portmanteau of scan and anxiety. A desire to avoid feeling this fear can prompt survivors to postpone or refuse tests.[41][42] This may be able to be helped by the follow-up of people who have had cancer post-treatment being undertaken via self-reported patient-related outcome measures rather than follow-up visits, but there is not enough controlled research looking into this.[43]

Survivors of childhood cancer have a life expectancy up to 28% shorter than people in the general population.[44] Therefore, there is a need to closely monitor these patients for much longer than usual. The Children's Oncology Group recommends that monitoring should include periodic follow-up and screening by a clinician familiar with these patients' risks. Improving these patients' longevity requires recognition and treatment of illnesses associated with late effects in the decades after therapy for childhood cancer. For example, survivors of childhood cancer may have more difficulty than typical with breastfeeding and require more support to undertake this health-promoting activity.[45] Childhood cancer survivors are also at risk for developing kidney diseases.[46] Others experience various forms of heart disease. One challenge to achieving this goal is that childhood cancer survivors are both very adaptable and accustomed to denying difficulties; as a result, they tend to minimize their symptoms. Therefore, internists may not give them all the attention they need and thus the actual help they may need. Symptom management, health promotion, specific attention to psychosocial needs, and surveillance for recurrence and specific late effects of treatment are helpful.[44] Health behaviour interventions may be able to reduce the impact of some of the chronic issues cancer survivors face by improving their dietary intake.[47] Likewise, physical exercise training interventions may have positive effects on physical fitness, including cardio-respiratory fitness, muscle strength and health-related quality of life.[48]

Adolescent and young adult survivors

Adolescent and young adult (AYA) survivors, often defined as being between the ages of 15 and 39, have seen advancements in technology and modern medicine causing a dramatic increase in the number of AYA survivors. Prior to 1970, childhood cancer was considered a universally fatal disease. From 1995 to 2000, however, the 5-year survival rate for children diagnosed with cancer was 80%.[49] Significant progress has been built in the last 25 years as there are now approximately 270,000 survivors of pediatric cancer in the U.S., which translates to approximately 1 in every 640 young adults being a survivor of childhood cancer.[50][51] However, as studies have shown, as patient needs increase, the likelihood of having an unmet need also increases.[52] For the AYA population, 2 out of 3 childhood cancer survivors will develop a complication due to the therapy they received, and 1 out of 3 will develop serious or life-threatening complications, meaning they will need treatment and follow-up care.[53] In addition, AYAs may experience greater difficulties adhering to treatment, which may negatively impact future outcomes.[54]

An AYA survivor faces a variety of issues as a result of their cancer diagnosis and treatment that are unique to their particular age group which differentiate their survivor population from the adult survivor population. For example, AYA survivors report that their education, employment, sexual functioning,[55] marriage, fertility, and other life values are impacted by their cancer.[56][57] Compared to adult survivors, AYA survivors have a much greater risk of getting a second primary malignancy as a side effect of the treatment for their original diagnosis. It is believed that AYAs have a much higher relative risk of developing a second primary cancer because the intensity of the treatment for their original diagnosis, typically including any combination of chemotherapy, surgery, and radiation therapy, is much higher than the level of intensity given to patients over 40.[58] Furthermore, since AYA survivors are diagnosed and treated at such a young age, their length of time as a survivor is much longer than their adult counterparts, making it more likely they will face a second primary cancer in their lifetime.[58]

Barriers to quality long-term follow-up care

Childhood cancer survivors, in particular, need comprehensive long-term follow-up care to thrive. One way this can be accomplished is through continuous follow-up care with a primary care physician who is trained to identify possible late effects from previous treatments and therapies.[59]

The Children's Oncology Group (COG) has designed a set of survivorship guidelines that hope to aid both health care professionals and survivors themselves, in both the intricacies and basics of long-term follow-up care. The COG recommends that patients or their families put together their own treatment summary, so they can have their treatment history with them when they visit any health care provider. The COG suggests that all survivors include the following in their treatment summaries:

  • Name of disease, date of diagnosis, stage of disease, contact information of all clinics and hospitals where care was received
  • Names and doses of any chemotherapy received
  • Names and doses of any radiation received, and the area of the body that was radiated
  • Names and dates of all surgeries
  • For people receiving a transplant, the type of transplant, where it was received, and whether chronic graft-versus-host disease developed
  • Names and dates of any significant complications and treatment received for those complications[60]

With the treatment summary, experts hope that survivors will be better equipped to maintain quality follow-up care long after their original treatment. This is especially important for the AYA population, in particular, because they are typically facing major social changes regarding their relationship status, employment or education status, their insurance coverage, and even their place of residence, etc. Typically, most of these factors are stable for most older adults, and when they experience any changes, it would usually occur in one or two aspects of their life at a time. However, with people under the age of 40 is when most people undergo the most change. This reality underscores the importance of a smooth transition from child-centered to adult-focused health care services through which they are consistently managed.[61]

Impact of Affordable Care Act on the AYA survivor population

The US Affordable Care Act (ACA) in 2010 makes it illegal for health insurance providers to deny coverage for a pre-existing condition, such as previously having survived cancer.[62] Young adults are required to have health insurance coverage and, with a few exceptions, will be able to be covered under their parent's coverage until the age of 26 as a dependent in their parent's plan.[62]

Care

Studies among endometrial cancer survivors show that satisfaction with information provided about the disease and treatment increases the quality of life, lowers depression and results in less anxiety.[63] People who receive information on paper, compared to oral, indicate that they receive more information and are more satisfied about the information provided.[64] The US Institute of Medicine and the Dutch Health Council recommend the use of a written "survivorship care plan", which is a summary of a patient's course of treatment, with recommendations for subsequent surveillance, management of late effects, and strategies for health promotion.[65]

Cancer survivors are encouraged to meet the same guidelines for physical activity as the rest of the population.[66][67] However, less than one-third of US cancer survivors met the Physical Activity Guideline for Americans.[68] Increased physical activity reduces both all-cause and cancer-specific mortality in breast[69] and colorectal cancer survivors[70] as well as all cancer survivors.[68] In addition, sedentary behaviors, particularly prolonged sitting, were associated with worse survival outcomes.[68] Physical activity improves quality of life among a range of cancer survivors[71] and may also assist with cancer-related fatigue and common co-morbidities.[72][73]

Diet can also impact long-term mortality, with evidence across various cancer types.[74][75][76][77]

However, adherence to diet and exercise recommendations among cancer survivors is often poor.[78][79][80]

Digital behaviour change interventions can be successful at increasing physical activity and may also help with diet in cancer survivors.[81]

In breast cancer survivors, home-based multidimensional survivorship programmes have short-term beneficial impacts on quality of life and can reduce anxiety, fatigue and insomnia.[82] Mindfulness-based survivorship programs may be an effective way to improve the mental health of cancer survivors.[83][84]

Family members

Family members can be significantly affected by the cancer experience of their loved ones.[85][86] For parents of children with cancer, finishing treatment can be a particularly vulnerable time. In the post-treatment period, some parents may experience increases in anxiety, depression and feelings of helplessness.[87] A sub-group of parents report post-traumatic stress symptoms up to years after treatment completion.[88] Evidence-based psychological interventions tailored to the needs of parents of childhood cancer survivors may assist parents in resuming their normal lives after their child has finished treatment.[89]

Spouses of cancer survivors are more likely than other people to experience anxiety in the years after their partner's successful treatment.[29] Being married reduces the cancer survivor's risk of developing post-traumatic stress disorder or other psychological difficulties, but it increases the risk of the spouse developing mental health symptoms.[23]

See also

Notes

  1. ↑ Sulik was writing specifically about women survivors of breast cancer.

References

  1. ↑ "Genetic correlates of Chinese medicine: in search of a common language". Journal of Alternative and Complementary Medicine 13 (2): 183–4. March 2007. doi:10.1089/act.2007.13406. PMID 17388756. 
  2. ↑ 2.0 2.1 "Cancer survivors face psychological challenges". Sun-Sentinel (Fort Lauderdale, Florida). 22 January 2009. http://www.allbusiness.com/medicine-health/diseases-disorders-cancer/11927794-1.html. 
  3. ↑ 3.0 3.1 3.2 3.3 3.4 3.5 3.6 Pink Ribbon Blues: How Breast Cancer Culture Undermines Women's Health. USA: Oxford University Press. 2010. ISBN 978-0-19-974045-1. OCLC 535493589. https://archive.org/details/pinkribbonbluesh0000suli. 
  4. ↑ Psychological aspects of cancer a guide to emotion and psychological consequences of cancer, their causes and their management. New York: Springer. 2013. p. 167. ISBN 9781461448662. 
  5. ↑ "Living with or beyond cancer". Macmillan Cancer Support. http://www.macmillan.org.uk/GetInvolved/Campaigns/Survivorship/Livingwithorbeyondcancer.aspx. 
  6. ↑ "DCCPS: OCS: About Cancer Survivorship Research: Survivorship Definitions". Office of Cancer Survivorship of the US National Cancer Institute. 6 November 2006. http://cancercontrol.cancer.gov/ocs/definitions.html. 
  7. ↑ "Definitions". Office of Cancer Survivorship, Division of Cancer Control and Population Sciences (DCCPS), National Cancer Institute. 17 November 2022. https://cancercontrol.cancer.gov/ocs/definitions. 
  8. ↑ "The DNA Age, Cancer Free at Age 33, but Weighing a Mastectomy". The New York Times. 16 September 2007. https://www.nytimes.com/2007/09/16/health/16gene.html. 
  9. ↑ "FORCE | Special Populations : Cancer Previvors". http://facingourrisk.org/pre-vivors_and_survivors/cancer_pre-vivors.html. 
  10. ↑ "Living with cancer". Macmillan Cancer Support. http://www.macmillan.org.uk/GetInvolved/Campaigns/Survivorship/Macmillan_and_survivorship.aspx. 
  11. ↑ 11.0 11.1 "Cancer-related fatigue: prevalence, assessment and treatment strategies". Expert Review of Pharmacoeconomics & Outcomes Research 11 (4): 441–6. August 2011. doi:10.1586/erp.11.44. PMID 21831025. 
  12. ↑ "Sleep problems in cancer patients: prevalence and association with distress and pain". Psycho-Oncology 21 (9): 1003–9. September 2012. doi:10.1002/pon.2004. PMID 21726015. 
  13. ↑ "Lymphedema after breast cancer: incidence, risk factors, and effect on upper body function". Journal of Clinical Oncology 26 (21): 3536–42. July 2008. doi:10.1200/JCO.2007.14.4899. PMID 18640935. 
  14. ↑ "Weight Change and Associated Factors in Long-Term Breast Cancer Survivors". PLOS ONE 11 (7): e0159098. 2016. doi:10.1371/journal.pone.0159098. PMID 27391162. Bibcode: 2016PLoSO..1159098K. 
  15. ↑ "Prevalence of depression in cancer patients: a meta-analysis of diagnostic interviews and self-report instruments". Psycho-Oncology 23 (2): 121–30. February 2014. doi:10.1002/pon.3409. PMID 24105788. 
  16. ↑ "Fear of cancer recurrence in adult cancer survivors: a systematic review of quantitative studies". Journal of Cancer Survivorship 7 (3): 300–22. September 2013. doi:10.1007/s11764-013-0272-z. PMID 23475398. 
  17. ↑ "The effects of age on health-related quality of life in cancer populations: A pooled analysis of randomized controlled trials using the European Organisation for Research and Treatment of Cancer (EORTC) QLQ-C30 involving 6024 cancer patients". European Journal of Cancer 51 (18): 2808–19. December 2015. doi:10.1016/j.ejca.2015.08.027. PMID 26602015. http://eprints.whiterose.ac.uk/92305/7/Quinten%20Final_manuscript_Age_Cancer_Burden_EORTC%20.pdf. 
  18. ↑ "Losing a Comforting Ritual: Treatment". The New York Times. 29 June 2009. https://www.nytimes.com/2009/06/30/health/30case.html. 
  19. ↑ Meeting Psychosocial Needs of Women with Breast Cancer. Maria Elizabeth Hewitt, Roger Herdman, Jimmie C. Holland, National Cancer Policy Board, Institute of Medicine, National Research Council. Washington, D.C.: National Academies Press. 2004. pp. 28–29. ISBN 0-309-52953-0. OCLC 55636077. 
  20. ↑ Holland, Jimmie C.; Zittoun, Robert (2012-12-06) (in en). Psychosocial Aspects of Oncology. Springer Science & Business Media. pp. 30. ISBN 978-3-642-46695-3. https://books.google.com/books?id=v-L7CAAAQBAJ&dq=cancer+dependent+on+attention+sympathy&pg=PA30. 
  21. ↑ "Marital satisfaction of advanced prostate cancer survivors and their spousal caregivers: the dyadic effects of physical and mental health". Psycho-Oncology 20 (12): 1353–7. December 2011. doi:10.1002/pon.1855. PMID 20925137. 
  22. ↑ "Longitudinal effects of social support and adaptive coping on the emotional well-being of survivors of localized prostate cancer". The Journal of Supportive Oncology 8 (5): 196–201. 2010. doi:10.1016/j.suponc.2010.09.004. PMID 21086876. 
  23. ↑ 23.0 23.1 Feuerstein, Michael (2007-10-18) (in en). Handbook of Cancer Survivorship. Springer Science & Business Media. pp. 33. ISBN 978-0-387-34562-8. https://books.google.com/books?id=OsMwPsFIAAQC. 
  24. ↑ 24.0 24.1 "Remy's woes befall many after cancer: Depression can hit as survivors adjust". Boston Globe. 14 August 2009. http://www.boston.com/news/health/articles/2009/08/14/depression_that_hit_remy_befalls_many_after_cancer/. 
  25. ↑ 25.0 25.1 "Psychological distress in long-term survivors of adult-onset cancer: results from a national survey". Archives of Internal Medicine 169 (14): 1274–81. July 2009. doi:10.1001/archinternmed.2009.179. PMID 19636028. 
  26. ↑ "Post-traumatic stress disorder in childhood cancer survivors: how common is it?". Journal of the National Cancer Institute 93 (4): 262–3. February 2001. doi:10.1093/jnci/93.4.262. PMID 11181770. 
  27. ↑ "Suicide ideation in adult survivors of childhood cancer: a report from the Childhood Cancer Survivor Study". Journal of Clinical Oncology 28 (4): 655–61. February 2010. doi:10.1200/JCO.2009.22.8635. PMID 19841325. 
  28. ↑ "Suicidal ideation and attempts in adult survivors of childhood cancer". Journal of Clinical Oncology 24 (24): 3852–7. August 2006. doi:10.1200/JCO.2006.06.5409. PMID 16921037. 
  29. ↑ 29.0 29.1 "Depression and anxiety in long-term cancer survivors compared with spouses and healthy controls: a systematic review and meta-analysis". The Lancet. Oncology 14 (8): 721–32. July 2013. doi:10.1016/S1470-2045(13)70244-4. PMID 23759376. 
  30. ↑ "A qualitative exploration of fear of cancer recurrence (FCR) amongst Australian and Canadian breast cancer survivors". Supportive Care in Cancer 24 (5): 2269–2276. May 2016. doi:10.1007/s00520-015-3025-x. PMID 26581900. 
  31. ↑ "Triggers of uncertainty about recurrence and long-term treatment side effects in older African American and Caucasian breast cancer survivors". Oncology Nursing Forum 31 (3): 633–9. May 2004. doi:10.1188/04.ONF.633-639. PMID 15146229. 
  32. ↑ "Follow-up practice in endometrial cancer and the association with patient and hospital characteristics: a study from the population-based PROFILES registry". Gynecologic Oncology 129 (2): 324–31. May 2013. doi:10.1016/j.ygyno.2013.02.018. PMID 23435365. 
  33. ↑ 33.0 33.1 "Fear of progression in patients with gastrointestinal stromal tumors (GIST): Is extended lifetime related to the Sword of Damocles?". Acta Oncologica 54 (8): 1202–8. 2015-09-14. doi:10.3109/0284186X.2014.1003960. PMID 25734906. 
  34. ↑ "Fear of cancer recurrence: a systematic literature review of self-report measures". Psycho-Oncology 21 (6): 571–87. June 2012. doi:10.1002/pon.2070. PMID 22021099. 
  35. ↑ "Study protocol of the SWORD-study: a randomised controlled trial comparing combined online and face-to-face cognitive behaviour therapy versus treatment as usual in managing fear of cancer recurrence". BMC Psychology 3 (1): 12. 2015. doi:10.1186/s40359-015-0068-1. PMID 25977758. 
  36. ↑ "Conquer fear: protocol of a randomised controlled trial of a psychological intervention to reduce fear of cancer recurrence". BMC Cancer 13 (1): 201. April 2013. doi:10.1186/1471-2407-13-201. PMID 23617696. 
  37. ↑ "Protocol of a randomized controlled trial of the fear of recurrence therapy (FORT) intervention for women with breast or gynecological cancer". BMC Cancer 16 (1): 291. April 2016. doi:10.1186/s12885-016-2326-x. PMID 27112319. 
  38. ↑ "A Smartphone App-Based Mindfulness Intervention for Cancer Survivors: Protocol for a Randomized Controlled Trial". JMIR Research Protocols 9 (5): e15178. May 2020. doi:10.2196/15178. PMID 32390591. 
  39. ↑ "A randomized dose-response trial of aerobic exercise and health-related quality of life in colon cancer survivors". Psycho-Oncology 27 (4): 1221–1228. April 2018. doi:10.1002/pon.4655. PMID 29388275. 
  40. ↑ "'Survivor plans' a long-term cancer-treatment strategy". Associated Press. 23 October 2007. http://blog.mlive.com/kalamazoo_gazette_extra/2007/10/survivor_plans_a_longterm_canc.html. 
  41. ↑ "Chapter 9" (in en). Social Work in Health Settings: Practice in Context. Routledge. 2016-03-02. ISBN 9781317409113. https://books.google.com/books?id=eFqpCwAAQBAJ. 
  42. ↑ "Scanxiety. Fear of a postcancer ritual". Time 177 (24): 56. June 2011. PMID 21682131. http://content.time.com/time/specials/packages/article/0,28804,2075133_2075127_2075107,00.html. 
  43. ↑ "Patient-reported outcome measures for follow-up after gynaecological cancer treatment". The Cochrane Database of Systematic Reviews 2022 (11): CD010299. November 2013. doi:10.1002/14651858.cd010299.pub2. PMID 24249483. 
  44. ↑ 44.0 44.1 "A model-based estimate of cumulative excess mortality in survivors of childhood cancer". Annals of Internal Medicine 152 (7): 409–17, W131-8. April 2010. doi:10.7326/0003-4819-152-7-201004060-00005. PMID 20368646. 
  45. ↑ "Protective effects of breastfeeding for mothers surviving childhood cancer". Journal of Cancer Survivorship 5 (2): 175–81. June 2011. doi:10.1007/s11764-010-0169-z. PMID 21253880. 
  46. ↑ "Early and late adverse renal effects after potentially nephrotoxic treatment for childhood cancer". The Cochrane Database of Systematic Reviews 2019 (3): CD008944. March 2019. doi:10.1002/14651858.cd008944.pub3. PMID 30855726. 
  47. ↑ "Nutritional interventions for survivors of childhood cancer". The Cochrane Database of Systematic Reviews 2016 (8): CD009678. August 2016. doi:10.1002/14651858.cd009678.pub2. PMID 27545902. 
  48. ↑ "Physical exercise training interventions for children and young adults during and after treatment for childhood cancer". The Cochrane Database of Systematic Reviews 2017 (3): CD008796. March 2016. doi:10.1002/14651858.cd008796.pub3. PMID 27030386. 
  49. ↑ "SEER cancer statistics review, 1975-2001". National Cancer Institute. 2004. 
  50. ↑ "Comprehensive long-term follow-up programs for pediatric cancer survivors". Cancer 107 (4): 841–8. August 2006. doi:10.1002/cncr.22096. PMID 16886175. 
  51. ↑ Childhood cancer survivorship: Improving care and quality of life. Washington, D.C.: National Academies Press. 2003. https://archive.org/details/isbn_9780309088985. 
  52. ↑ "Living with cancer: the Cancer Inventory of Problem Situations". Journal of Clinical Psychology 40 (4): 972–80. July 1984. doi:10.1002/1097-4679(198407)40:4<972::aid-jclp2270400417>3.0.co;2-w. PMID 6480863. 
  53. ↑ "Long-term complications following childhood and adolescent cancer: foundations for providing risk-based health care for survivors". CA: A Cancer Journal for Clinicians 54 (4): 208–36. 2004. doi:10.3322/canjclin.54.4.208. PMID 15253918. 
  54. ↑ "Review of adherence-related issues in adolescents and young adults with cancer". Journal of Clinical Oncology 28 (32): 4800–4809. November 2010. doi:10.1200/JCO.2009.22.2802. PMID 20212260. 
  55. ↑ "Sexual function in childhood cancer survivors: a report from Project REACH". The Journal of Sexual Medicine 10 (8): 2084–93. August 2013. doi:10.1111/jsm.12193. PMID 23679087. 
  56. ↑ "Quality of life issues and cancer survivorship". Current Problems in Cancer 27 (4): 198–211. 2003. doi:10.1016/s0147-0272(03)00027-8. PMID 12855951. 
  57. ↑ "Sexual and Romantic Relationships: Experiences of Adolescent and Young Adult Cancer Survivors". Journal of Adolescent and Young Adult Oncology 5 (3): 286–91. September 2016. doi:10.1089/jayao.2015.0061. PMID 26885746. 
  58. ↑ 58.0 58.1 "Current issues in adolescent and young adult cancer survivorship". Cancer Control 15 (1): 55–62. January 2008. doi:10.1177/107327480801500107. PMID 18094661. 
  59. ↑ American Academy of Pediatrics Section on Hematology/Oncology Children's Oncology Group (March 2009). "Long-term follow-up care for pediatric cancer survivors". Pediatrics 123 (3): 906–15. doi:10.1542/peds.2008-3688. PMID 19255020. 
  60. ↑ "Introduction to Long-term Follow-Up after Treatment for Childhood, Adolescent, or Young Adult Cancer". Children's Oncology Group. 2008. http://www.survivorshipguidelines.org//pdf/introductiontoLong-TermFollow-Up.pdf. 
  61. ↑ "Transition of care for young adult survivors of childhood and adolescent cancer: rationale and approaches". Journal of Clinical Oncology 28 (32): 4810–8. November 2010. doi:10.1200/jco.2009.23.4278. PMID 20351333. 
  62. ↑ 62.0 62.1 "Summary of New Health Reform Law". Kaiser Family Foundation. http://www.kff.org/healthreform/upload/8061.pdf. 
  63. ↑ "The relation between information provision and health-related quality of life, anxiety and depression among cancer survivors: a systematic review". Annals of Oncology 22 (4): 761–72. April 2011. doi:10.1093/annonc/mdq413. PMID 20870912. 
  64. ↑ "Endometrial cancer survivors are unsatisfied with received information about diagnosis, treatment and follow-up: a study from the population-based PROFILES registry". Patient Education and Counseling 88 (3): 427–35. September 2012. doi:10.1016/j.pec.2012.05.002. PMID 22658248. https://pure.uvt.nl/ws/files/1435545/MedPsy_Nicolaije_Endometrial_PEaC_2012.pdf. 
  65. ↑ "The impact of a cancer Survivorship Care Plan on gynecological cancer patient and health care provider reported outcomes (ROGY Care): study protocol for a pragmatic cluster randomized controlled trial". Trials 12: 256. December 2011. doi:10.1186/1745-6215-12-256. PMID 22141750. 
  66. ↑ "Physical activity guidelines for Americans.". U.S. Department of Health and Human Services.. 2008. https://health.gov/paguidelines/pdf/paguide.pdf. 
  67. ↑ "American College of Sports Medicine roundtable on exercise guidelines for cancer survivors". Medicine and Science in Sports and Exercise 42 (7): 1409–26. July 2010. doi:10.1249/MSS.0b013e3181e0c112. PMID 20559064. 
  68. ↑ 68.0 68.1 68.2 "Association of Daily Sitting Time and Leisure-Time Physical Activity With Survival Among US Cancer Survivors". JAMA Oncology 8 (3): 395–403. March 2022. doi:10.1001/jamaoncol.2021.6590. PMID 34989765. 
  69. ↑ "Physical activity, risk of death and recurrence in breast cancer survivors: A systematic review and meta-analysis of epidemiological studies". Acta Oncologica 54 (5): 635–54. May 2015. doi:10.3109/0284186X.2014.998275. PMID 25752971. 
  70. ↑ Schmid D, Leitzmann MF. Association between physical activity and mortality among breast cancer and colorectal cancer survivors: a systematic review and meta-analysis. Ann Oncol. 2014;25(7):1293–311.
  71. ↑ Mishra SI, Scherer RW, Geigle PM, et al. Exercise interventions on health-related quality of life for cancer survivors. Cochrane Database Syst Rev. 2012;8:CD007566.
  72. ↑ "Associations of sedentary time and patterns of sedentary time accumulation with health-related quality of life in colorectal cancer survivors". Preventive Medicine Reports 4: 262–9. December 2016. doi:10.1016/j.pmedr.2016.06.022. PMID 27419042. 
  73. ↑ "Correlates of objectively measured sedentary behavior in breast cancer survivors". Cancer Causes & Control 27 (6): 787–95. June 2016. doi:10.1007/s10552-016-0756-z. PMID 27146839. 
  74. ↑ "Effect of low-fat diet on breast cancer survival: a meta-analysis". Asian Pacific Journal of Cancer Prevention 15 (3): 1141–4. 2014. doi:10.7314/apjcp.2014.15.3.1141. PMID 24606431. 
  75. ↑ "Dietary fat and breast cancer mortality: A systematic review and meta-analysis". Critical Reviews in Food Science and Nutrition 57 (10): 1999–2008. July 2017. doi:10.1080/10408398.2012.724481. PMID 25692500. https://pureadmin.qub.ac.uk/ws/files/120387796/Dietary_fat_and_breast_cancer_mortality_A_systematic_review_and_meta_analysis.pdf. 
  76. ↑ "Association of dietary patterns with cancer recurrence and survival in patients with stage III colon cancer". JAMA 298 (7): 754–64. August 2007. doi:10.1001/jama.298.7.754. PMID 17699009. 
  77. ↑ "Adherence to Mediterranean diet and risk of cancer: an updated systematic review and meta-analysis of observational studies". Cancer Medicine 4 (12): 1933–47. December 2015. doi:10.1002/cam4.539. PMID 26471010. 
  78. ↑ "Adherence to the World Cancer Research Fund/American Institute for Cancer Research lifestyle recommendations in colorectal cancer survivors: results of the PROFILES registry". Cancer Medicine 5 (9): 2587–95. September 2016. doi:10.1002/cam4.791. PMID 27418442. 
  79. ↑ "Cancer survivors' adherence to lifestyle behavior recommendations and associations with health-related quality of life: results from the American Cancer Society's SCS-II". Journal of Clinical Oncology 26 (13): 2198–204. May 2008. doi:10.1200/JCO.2007.14.6217. PMID 18445845. 
  80. ↑ "Is a cancer diagnosis a trigger for health behaviour change? Findings from a prospective, population-based study". British Journal of Cancer 108 (11): 2407–12. June 2013. doi:10.1038/bjc.2013.254. PMID 23695026. 
  81. ↑ "Digital health behaviour change interventions targeting physical activity and diet in cancer survivors: a systematic review and meta-analysis". Journal of Cancer Survivorship 11 (6): 704–719. December 2017. doi:10.1007/s11764-017-0632-1. PMID 28779220. 
  82. ↑ "Home-based multidimensional survivorship programmes for breast cancer survivors". The Cochrane Database of Systematic Reviews 2017 (8): CD011152. August 2017. doi:10.1002/14651858.cd011152.pub2. PMID 28836379. 
  83. ↑ "Mindfulness-based stress reduction for breast cancer-a systematic review and meta-analysis". Current Oncology 19 (5): e343-52. October 2012. doi:10.3747/co.19.1016. PMID 23144582. PMC 3457885. https://www.current-oncology.com/index.php/oncology/article/view/1016. 
  84. ↑ "The efficacy of mindfulness-based stress reduction on mental health of breast cancer patients: a meta-analysis". Psycho-Oncology 22 (7): 1457–65. July 2013. doi:10.1002/pon.3171. PMID 22961994. 
  85. ↑ "Physical, psychosocial, relationship, and economic burden of caring for people with cancer: a review". Journal of Oncology Practice 9 (4): 197–202. July 2013. doi:10.1200/JOP.2012.000690. PMID 23942921. 
  86. ↑ "'What they're not telling you': a new scale to measure grandparents' information needs when their grandchild has cancer". Patient Education and Counseling 94 (3): 351–5. March 2014. doi:10.1016/j.pec.2013.10.030. PMID 24315159. 
  87. ↑ "Psychological adjustment of parents of pediatric cancer patients revisited: five years later". Psycho-Oncology 15 (1): 1–8. January 2006. doi:10.1002/pon.927. PMID 15880477. https://www.rug.nl/research/portal/en/publications/psychological-adjustment-of-parents-of-pediatric-cancer-patients-revisited(e9249a8a-c4e9-478d-92e5-909bc886356e).html. 
  88. ↑ "Long-term positive and negative psychological late effects for parents of childhood cancer survivors: a systematic review". PLOS ONE 9 (7): e103340. 2014-07-24. doi:10.1371/journal.pone.0103340. PMID 25058607. Bibcode: 2014PLoSO...9j3340L. 
  89. ↑ "Online parent-targeted cognitive-behavioural therapy intervention to improve quality of life in families of young cancer survivors: study protocol for a randomised controlled trial" (in En). Trials 16 (1): 153. April 2015. doi:10.1186/s13063-015-0681-6. PMID 25872773. 

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