Medicine:Cervical conization
| Cervical conization | |
|---|---|
| ICD-9-CM | 67.2 |
Cervical conization refers to an excision of a cone-shaped portion of tissue from the mucous membrane of the cervix. Conization is used for diagnostic purposes as part of a biopsy and for therapeutic purposes to remove pre-cancerous cells (cervical intraepithelial neoplasia) or early stage cervical cancer.[1]
- Cold knife conization (CKC)
- Laser conization
- Loop electrical excision procedure (LEEP)
Side effects
Cervical conization effectively reduces the risk of cancer developing or spreading but it causes an increased risk of premature birth in future pregnancies.[2][3]
The chances of cancer recurrence and premature birth depends on the type of conization. Cold knife conization is associated with 7% chance of the cancer recurring and 16% chance of premature birth, laser conisation comes with 6% cancer recurrence and 13% premature birth, and loop excision comes with 10% recurrence and 11% premature birth.[2][3]
See also
- Cervicectomy
References
- ↑ Cooper, Danielle B.; Carugno, Jose; Menefee, Gary W. (2023), "Conization of Cervix", StatPearls (Treasure Island (FL): StatPearls Publishing), PMID 28722875, http://www.ncbi.nlm.nih.gov/books/NBK441845/, retrieved 2023-11-16
- ↑ 2.0 2.1 2.2 Athanasiou, Antonios; Veroniki, Areti Angeliki; Efthimiou, Orestis; Kalliala, Ilkka; Naci, Huseyin; Bowden, Sarah; Paraskevaidi, Maria; Arbyn, Marc et al. (2022-07-25). "Comparative effectiveness and risk of preterm birth of local treatments for cervical intraepithelial neoplasia and stage IA1 cervical cancer: a systematic review and network meta-analysis" (in en). The Lancet Oncology 23 (8): 1097–1108. doi:10.1016/S1470-2045(22)00334-5. PMID 35835138. PMC 9630146. https://linkinghub.elsevier.com/retrieve/pii/S1470204522003345.
- ↑ 3.0 3.1 3.2 "Prevention of cervical cancer: what are the risks and benefits of different treatments?". NIHR Evidence (National Institute for Health and Care Research). 2023-11-10. doi:10.3310/nihrevidence_60599. https://evidence.nihr.ac.uk/alert/prevention-of-cervical-cancer-what-are-the-risks-and-benefits-of-different-treatments/.
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