Medicine:Hexaminolevulinate
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Short description: Optical imaging agent
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| Trade names | Cysview, Hexvix |
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Hexaminolevulinate, sold under the brand names Cysview and Hexvix, is an imaging agent that lights up under blue light during a blue light cystoscopy. It is used to help detect non-muscle invasive bladder cancer (NMIBC), in particular papillary tumors and carcinoma in situ (CIS).
It made by Photocure ASA, a Norwegian pharmaceutical company.
Hexaminolevulinate is a structural analogue to 5-aminolevulinic acid (a precursor to the porphyrin ring of heme), and is internalized and processed into the photoactive protoporphyrin IX at a high rate by tumor cells. After exposure to 360-450 nm light, the porphyrin will fluoresce red.[1]
References
- ↑ "Prescription medicines: registration of new chemical entities in Australia, 2016". 21 June 2022. https://www.tga.gov.au/prescription-medicines-registration-new-chemical-entities-australia-2016.
- ↑ "Cysview- hexaminolevulinate hydrochloride kit". 15 November 2022. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=5aeed40d-6841-4adf-8940-f51d439fdfa3.
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