Biology:4-Hydroxycoumarin synthase
From HandWiki
Short description: Class of enzymes
| 4-hydroxycoumarin synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.3.1.208 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
4-hydroxycoumarin synthase (EC 2.3.1.208, BIS2, BIS3) is an enzyme with systematic name malonyl-CoA:2-hydroxybenzoyl-CoA malonyltransferase.[1] This enzyme catalyses the following chemical reaction
- malonyl-CoA + 2-hydroxybenzoyl-CoA [math]\displaystyle{ \rightleftharpoons }[/math] 2 CoA + 4-hydroxycoumarin + CO2
This polyketide synthase can also accept benzoyl-CoA as substrate.
References
- ↑ "A novel 4-hydroxycoumarin biosynthetic pathway". Plant Molecular Biology 72 (1–2): 17–25. January 2010. doi:10.1007/s11103-009-9548-0. PMID 19757094.
External links
- 4-hydroxycoumarin+synthase at the US National Library of Medicine Medical Subject Headings (MeSH)
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