Biology:Acetyl-S-ACP:malonate ACP transferase
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Short description: Class of enzymes
| Acetyl-S-ACP:malonate ACP transferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.3.1.187 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Acetyl-S-ACP:malonate ACP transferase (EC 2.3.1.187, acetyl-S-ACP:malonate ACP-SH transferase, acetyl-S-acyl-carrier protein:malonate acyl-carrier-protein-transferase, MdcA, MadA, ACP transferase, malonate/acetyl-CoA transferase, malonate:ACP transferase, acetyl-S-acyl carrier protein:malonate acyl carrier protein-SH transferase) is an enzyme with systematic name acetyl-(acyl-carrier-protein):malonate S-(acyl-carrier-protein)transferase.[1][2][3][4][5] This enzyme catalyses the following chemical reaction
- acetyl-[acyl-carrier protein] + malonate [math]\displaystyle{ \rightleftharpoons }[/math] malonyl-[acyl-carrier protein] + acetate
This is the first step in the catalysis of malonate decarboxylation.
References
- ↑ "Purification and characterization of a cytoplasmic enzyme component of the Na+-activated malonate decarboxylase system of Malonomonas rubra: acetyl-S-acyl carrier protein: malonate acyl carrier protein-SH transferase". Archives of Microbiology 162 (1-2): 48–56. 1994. doi:10.1007/bf00264372. PMID 18251085.
- ↑ "Sequence of a gene cluster from Klebsiella pneumoniae encoding malonate decarboxylase and expression of the enzyme in Escherichia coli". European Journal of Biochemistry 246 (2): 530–8. June 1997. doi:10.1111/j.1432-1033.1997.00530.x. PMID 9208947.
- ↑ "Functional evaluation of the genes involved in malonate decarboxylation by Acinetobacter calcoaceticus". European Journal of Biochemistry 266 (2): 683–90. December 1999. doi:10.1046/j.1432-1327.1999.00924.x. PMID 10561613.
- ↑ "Functions of malonate decarboxylase subunits from Pseudomonas putida". Bioscience, Biotechnology, and Biochemistry 67 (1): 214–7. January 2003. doi:10.1271/bbb.67.214. PMID 12619701.
- ↑ "Enzymic and genetic basis for bacterial growth on malonate". Molecular Microbiology 25 (1): 3–10. July 1997. doi:10.1046/j.1365-2958.1997.4611824.x. PMID 11902724.
External links
- Acetyl-S-ACP:malonate+ACP+transferase at the US National Library of Medicine Medical Subject Headings (MeSH)
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