Biology:ATP diphosphatase
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Short description: Class of enzymes
| ATP diphosphatase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.6.1.8 | ||||||||
| CAS number | 37289-25-1 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, an ATP diphosphatase (EC 3.6.1.8) is an enzyme that catalyzes the chemical reaction
- ATP + H2O [math]\displaystyle{ \rightleftharpoons }[/math] AMP + diphosphate
Thus, the two substrates of this enzyme are ATP and H2O, whereas its two products are AMP and diphosphate.
This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides in phosphorus-containing anhydrides. The systematic name of this enzyme class is ATP diphosphohydrolase (diphosphate-forming). Other names in common use include ATPase, ATP pyrophosphatase, adenosine triphosphate pyrophosphatase, and ATP diphosphohydrolase [ambiguous]. This enzyme participates in purine metabolism and pyrimidine metabolism.
References
- "Mechanism of enzymatic hydrolysis of adenosinetriphosphate". J. Biol. Chem. 202 (1): 217–26. 1953. PMID 13061448.
- "Enzymic hydrolysis of adenosine phosphates by cobra venom". Biochem. J. 54 (4): 625–9. 1953. PMID 13058963.
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