Biology:Cysteine-S-conjugate N-acetyltransferase
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cysteine-S-conjugate N-acetyltransferase | |||||||||
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Identifiers | |||||||||
EC number | 2.3.1.80 | ||||||||
CAS number | 81725-80-6 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a cysteine-S-conjugate N-acetyltransferase (EC 2.3.1.80) is an enzyme that catalyzes the chemical reaction
- acetyl-CoA + an S-substituted L-cysteine [math]\displaystyle{ \rightleftharpoons }[/math] CoA + an S-substituted N-acetyl-L-cysteine
Thus, the two substrates of this enzyme are acetyl-CoA and S-substituted L-cysteine, whereas its two products are CoA and S-substituted N-acetyl-L-cysteine.
This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:S-substituted L-cysteine N-acetyltransferase. This enzyme participates in glutathione metabolism.
References
- "Cysteine S-conjugate N-acetyltransferase from rat kidney microsomes". Mol. Pharmacol. 21 (2): 444–8. 1982. PMID 6892478.
Original source: https://en.wikipedia.org/wiki/Cysteine-S-conjugate N-acetyltransferase.
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