Biology:Tropine acyltransferase
From HandWiki
| Tropine acyltransferase | |||||||||
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| Identifiers | |||||||||
| EC number | 2.3.1.185 | ||||||||
| CAS number | 162535-29-7&title= 138440-79-6, 162535-29-7 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Tropine acyltransferase (EC 2.3.1.185, tropine:acyl-CoA transferase, acetyl-CoA:tropan-3-ol acyltransferase, tropine acetyltransferase, tropine tigloyltransferase, TAT) is an enzyme with systematic name acyl-CoA:tropine O-acyltransferase.[1][2][3][4] This enzyme catalyses the following chemical reaction
This enzyme exhibits absolute specificity for the endo/3alpha configuration found in tropine as pseudotropine.
References
- ↑ "The formation of 3 alpha- and 3 beta-acetoxytropanes by Datura stramonium transformed root cultures involves two acetyl-CoA-dependent acyltransferases". FEBS Letters 292 (1-2): 293–7. November 1991. doi:10.1016/0014-5793(91)80887-9. PMID 1959620.
- ↑ Robins, R.J.; Bachmann,P.; Peerless, A.C.J.; Rabot, S. (1994). "Esterification reactions in the biosynthesis of tropane alkaloids in transformed root cultures". Plant Cell Tissue Organ Cult. 38: 241–247. doi:10.1007/bf00033883.
- ↑ "Specificities of the enzymes of N-alkyltropane biosynthesis in Brugmansia and Datura". Phytochemistry 52 (5): 871–8. November 1999. doi:10.1016/S0031-9422(99)00293-9. PMID 10626376.
- ↑ "Functional genomic analysis of alkaloid biosynthesis in Hyoscyamus niger reveals a cytochrome P450 involved in littorine rearrangement". Chemistry & Biology 13 (5): 513–20. May 2006. doi:10.1016/j.chembiol.2006.03.005. PMID 16720272.
External links
- Tropine+acyltransferase at the US National Library of Medicine Medical Subject Headings (MeSH)
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