Biology:Biphenyl synthase
From HandWiki
| Biphenyl synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.3.1.177 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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In enzymology, a biphenyl synthase (EC 2.3.1.177) is an enzyme that catalyzes the chemical reaction:
- 3 malonyl-CoA + benzoyl-CoA [math]\displaystyle{ \rightleftharpoons }[/math] 4 CoA + 3,5-dihydroxybiphenyl + 4 CO2
Thus, the two substrates of this enzyme are malonyl-CoA and benzoyl-CoA, whereas its three products are CoA, 3,5-dihydroxybiphenyl, and CO2.
This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is malonyl-CoA:benzoyl-CoA malonyltransferase. This enzyme is also called BIS.
References
- "Biphenyl synthase from yeast-extract-treated cell cultures of Sorbus aucuparia". Planta 218 (3): 492–6. 2004. doi:10.1007/s00425-003-1144-y. PMID 14595561.
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