Biology:UDP-4-amino-4,6-dideoxy-N-acetyl-alpha-D-glucosamine N-acetyltransferase
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UDP-4-amino-4,6-dideoxy-N-acetyl-alpha-D-glucosamine N-acetyltransferase | |||||||||
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Identifiers | |||||||||
EC number | 2.3.1.203 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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UDP-4-amino-4,6-dideoxy-N-acetyl-alpha-D-glucosamine N-acetyltransferase (EC 2.3.1.203, PGLD) is an enzyme with systematic name acetyl-CoA:UDP-4-amino-4,6-dideoxy-N-acetyl-alpha-D-glucosamine N-acetyltransferase.[1][2][3] This enzyme catalyses the following chemical reaction
- acetyl-CoA + UDP-4-amino-4,6-dideoxy-N-acetyl-alpha-D-glucosamine [math]\displaystyle{ \rightleftharpoons }[/math] CoA + UDP-N,N'-diacetylbacillosamine
UDP-N,N'-diacetylbacillosamine is an intermediate in protein glycosylation pathways in several bacterial species.
References
- ↑ "In vitro biosynthesis of UDP-N,N'-diacetylbacillosamine by enzymes of the Campylobacter jejuni general protein glycosylation system". Biochemistry 45 (45): 13659–69. November 2006. doi:10.1021/bi061456h. PMID 17087520.
- ↑ "Structure and active site residues of PglD, an N-acetyltransferase from the bacillosamine synthetic pathway required for N-glycan synthesis in Campylobacter jejuni". Biochemistry 47 (7): 1827–36. February 2008. doi:10.1021/bi702032r. PMID 18198901.
- ↑ "Biochemical characterization of the O-linked glycosylation pathway in Neisseria gonorrhoeae responsible for biosynthesis of protein glycans containing N,N'-diacetylbacillosamine". Biochemistry 50 (22): 4936–48. June 2011. doi:10.1021/bi2003372. PMID 21542610.
External links
- UDP-4-amino-4,6-dideoxy-N-acetyl-alpha-D-glucosamine+N-acetyltransferase at the US National Library of Medicine Medical Subject Headings (MeSH)
![]() | Original source: https://en.wikipedia.org/wiki/UDP-4-amino-4,6-dideoxy-N-acetyl-alpha-D-glucosamine N-acetyltransferase.
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