Biology:(S)-scoulerine 9-O-methyltransferase
From HandWiki
Short description: Class of enzymes
| (S)-scoulerine 9-O-methyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.1.1.117 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a (S)-scoulerine 9-O-methyltransferase (EC 2.1.1.117) is an enzyme that catalyzes the chemical reaction
- S-adenosyl-L-methionine + (S)-scoulerine [math]\displaystyle{ \rightleftharpoons }[/math] S-adenosyl-L-homocysteine + (S)-tetrahydrocolumbamine
Thus, the two substrates of this enzyme are S-adenosyl methionine and (S)-scoulerine, whereas its two products are S-adenosylhomocysteine and (S)-tetrahydrocolumbamine.
This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:(S)-scoulerine 9-O-methyltransferase. This enzyme participates in alkaloid biosynthesis i.
References
- "S-Adenosyl-L-methionine:(S)-scoulerine 9-O-methyltransferase, a highly stereo- and regiospecific enzyme in tetrahydroberberine biosynthesis". Plant Cell Reports 4 (1): 36–39. 1985. doi:10.1007/BF00285501. PMID 24253642. http://nbn-resolving.de/urn:nbn:de:bvb:19-epub-3629-3.
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