Biology:CDP-glycerol diphosphatase

From HandWiki
Short description: Class of enzymes
CDP-glycerol diphosphatase
Identifiers
EC number3.6.1.16
CAS number37289-28-4
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

In enzymology, a CDP-glycerol diphosphatase (EC 3.6.1.16) is an enzyme that catalyzes the chemical reaction

CDP-glycerol + H2O [math]\displaystyle{ \rightleftharpoons }[/math] CMP + sn-glycerol 3-phosphate

Thus, the two substrates of this enzyme are CDP-glycerol and H2O, whereas its two products are CMP and sn-glycerol 3-phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides in phosphorus-containing anhydrides. The systematic name of this enzyme class is CDP-glycerol phosphoglycerohydrolase. Other names in common use include CDP-glycerol pyrophosphatase, and cytidine diphosphoglycerol pyrophosphatase. This enzyme participates in glycerophospholipid metabolism.

References

  • "The synthesis of teichoic acid IV. On the regulation of cytidine 5′-diphosphateglycerol concentration". Biochimica et Biophysica Acta (BBA) - Mucoproteins and Mucopolysaccharides 101: 6–15. March 1965. doi:10.1016/0926-6534(65)90025-4. PMID 14329291.