Biology:Deacetyl-(citrate-(pro-3S)-lyase) S-acetyltransferase
| deacetyl-[citrate-(pro-3S)-lyase] S-acetyltransferase | |||||||||
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| Identifiers | |||||||||
| EC number | 2.3.1.49 | ||||||||
| CAS number | 42616-18-2 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a deacetyl-[citrate-(pro-3S)-lyase] S-acetyltransferase (EC 2.3.1.49) is an enzyme that catalyzes the chemical reaction
- S-acetylphosphopantetheine + deacetyl-[citrate-oxaloacetate-lyase((pro-3S)-CH2COO-->acetate)] [math]\displaystyle{ \rightleftharpoons }[/math] phosphopantetheine + [citrate-oxaloacetate-lyase((pro-3S)-CH2COO-->acetate)]
Thus, the two substrates of this enzyme are S-acetylphosphopantetheine and deacetyl-[citrate-oxaloacetate-lyase((pro-3S)-CH2COO-->acetate)], whereas its two products are phosphopantetheine and citrate-oxaloacetate-lyase((pro-3S)-CH2COO-->acetate).
This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is S-acetylphosphopantetheine:deacetyl-[citrate-oxaloacetate-lyase((pro -3S)-CH2COO-->acetate)] S-acetyltransferase. Other names in common use include S-acetyl phosphopantetheine:deacetyl citrate lyase, S-acetyltransferase, and deacetyl-[citrate-(pro-3S)-lyase] acetyltransferase.
References
- "S-acetyl phosphopantetheine: deacetyl citrate lyase S-acetyl transferase from Klebsiella aerogenes". Biochem. Biophys. Res. Commun. 53 (1): 1–9. 1973. doi:10.1016/0006-291X(73)91392-2. PMID 4741546.
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