Biology:Dynamin superfamily
From HandWiki
Short description: Protein superfamily
| Dynamin superfamily | |
|---|---|
| Identifiers | |
| Symbol | DSP |
| InterPro | IPR022812 |
Dynamin Superfamily Protein (DSP) is a protein superfamily includes classical dynamins, GBPs, Mx proteins, OPA1, mitofusins in Eukaryote, and bacterial dynamin-like proteins (BDLPs) in Prokaryote.[1] DSPs mediate eukaryotic membrane fusion and fission necessary for endocytosis, organelle biogenesis and maintenance, Mitochondrial fusion and fission, as well as for prokaryotic cytokinesis.[2]
Structure
All DSPs have two common domains: a GTPase domain and an elongated α-helical bundle domain.[2]
References
- ↑ "Participation of dynamin in the biogenesis of cytoplasmic vesicles". FASEB Journal 13 Suppl 2 (9002): S243-7. December 1999. doi:10.1096/fasebj.13.9002.S243. PMID 10619136.
- ↑ 2.0 2.1 Jimah, JR; Hinshaw, JE (March 2019). "Structural Insights into the Mechanism of Dynamin Superfamily Proteins.". Trends in Cell Biology 29 (3): 257–273. doi:10.1016/j.tcb.2018.11.003. PMID 30527453.
External links
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