Biology:Flavonol-3-O-triglucoside O-coumaroyltransferase

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Flavonol-3-O-triglucoside O-coumaroyltransferase
Identifiers
EC number2.3.1.173
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

In enzymology, a flavonol-3-O-triglucoside O-coumaroyltransferase (EC 2.3.1.173) is an enzyme that catalyzes the chemical reaction

4-coumaroyl-CoA + a flavonol 3-O-[beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside] [math]\displaystyle{ \rightleftharpoons }[/math] CoA + a flavonol 3-O-[6-(4-coumaroyl)-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)- beta-D-glucoside]

The 3 substrates of this enzyme are 4-coumaroyl-CoA, flavonol, and 3-O-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside, whereas its 4 products are CoA, flavonol, 3-O-[6-(4-coumaroyl)-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-, and beta-D-glucoside].

This enzyme belongs to the family of transferases, to be specific those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is 4-coumaroyl-CoA:flavonol-3-O-[beta-D-glucosyl-(1->2)-beta-D-glucosid e] 6-O-4-coumaroyltransferase.

References

  • "Hydroxycinnamoyl: coenzyme A transferase involved in the biosynthesis of kaempferol-3-(p-coumaroyl triglucoside) in Pisum sativum". Z. Naturforsch. C 32 (9–10): 764–8. 1977. PMID 145116.