Biology:Glucosamine N-acetyltransferase

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glucosamine N-acetyltransferase
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Glucosamine N-acetyltransferase homodimer, Rhizomucor miehei
Identifiers
EC number2.3.1.3
CAS number9032-94-4
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

In enzymology, a glucosamine N-acetyltransferase (EC 2.3.1.3) is an enzyme that catalyzes the chemical reaction

acetyl-CoA + D-glucosamine [math]\displaystyle{ \rightleftharpoons }[/math] CoA + N-acetyl-D-glucosamine

Thus, the two substrates of this enzyme are acetyl-CoA and D-glucosamine, whereas its two products are CoA and N-acetyl-D-glucosamine.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:D-glucosamine N-acetyltransferase. Other names in common use include glucosamine acetylase, and glucosamine acetyltransferase. This enzyme participates in aminosugars metabolism.

References

  • "The acetylation of d-glucosamine by pigeon liver extracts". J. Biol. Chem. 196 (1): 105–9. 1952. PMID 12980946.