Biology:holA
From HandWiki
DNA polymerase III, delta subunit | |||||||
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Identifiers | |||||||
Organism | |||||||
Symbol | holA | ||||||
Entrez | 947573 | ||||||
RefSeq (Prot) | NP_415173.1 | ||||||
UniProt | P28630 | ||||||
Other data | |||||||
EC number | 2.7.7.7 | ||||||
Chromosome | genome: 0.67 - 0.67 Mb | ||||||
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DNA polymerase III, delta subunit | |||||||||
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![]() atpgs bound e. coli clamp loader complex | |||||||||
Identifiers | |||||||||
Symbol | DNA_pol3_delta | ||||||||
Pfam | PF06144 | ||||||||
Pfam clan | CL0023 | ||||||||
InterPro | IPR010372 | ||||||||
SCOP2 | 1jql / SCOPe / SUPFAM | ||||||||
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In molecular biology, holA is a gene that encodes the δ (delta) subunit of DNA polymerase III in E. coli and other bacteria. Along with the γ, δ', χ, and ψ subunits that make up the core polymerase, and the β accessory proteins, the δ subunit is responsible for the high speed and processivity of polIII.[1][2]
References
- ↑ "DNA polymerase III accessory proteins. I. holA and holB encoding delta and delta'". The Journal of Biological Chemistry 268 (16): 11758–65. June 1993. PMID 8505303. http://www.jbc.org/content/268/16/11758.full.pdf.
- ↑ "Molecular cloning, sequencing, and overexpression of the structural gene encoding the delta subunit of Escherichia coli DNA polymerase III holoenzyme". Journal of Bacteriology 174 (21): 7013–25. 1992. doi:10.1128/jb.174.21.7013-7025.1992. PMID 1400251.