Biology:holA
From HandWiki
| DNA polymerase III, delta subunit | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Organism | |||||||
| Symbol | holA | ||||||
| Entrez | 947573 | ||||||
| RefSeq (Prot) | NP_415173.1 | ||||||
| UniProt | P28630 | ||||||
| Other data | |||||||
| EC number | 2.7.7.7 | ||||||
| Chromosome | genome: 0.67 - 0.67 Mb | ||||||
| |||||||
| DNA polymerase III, delta subunit | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 atpgs bound e. coli clamp loader complex | |||||||||
| Identifiers | |||||||||
| Symbol | DNA_pol3_delta | ||||||||
| Pfam | PF06144 | ||||||||
| Pfam clan | CL0023 | ||||||||
| InterPro | IPR010372 | ||||||||
| SCOP2 | 1jql / SCOPe / SUPFAM | ||||||||
| |||||||||
In molecular biology, holA is a gene that encodes the δ (delta) subunit of DNA polymerase III in E. coli and other bacteria. Along with the γ, δ', χ, and ψ subunits that make up the core polymerase, and the β accessory proteins, the δ subunit is responsible for the high speed and processivity of polIII.[1][2]
References
- ↑ "DNA polymerase III accessory proteins. I. holA and holB encoding delta and delta'". The Journal of Biological Chemistry 268 (16): 11758–65. June 1993. PMID 8505303. http://www.jbc.org/content/268/16/11758.full.pdf.
- ↑ "Molecular cloning, sequencing, and overexpression of the structural gene encoding the delta subunit of Escherichia coli DNA polymerase III holoenzyme". Journal of Bacteriology 174 (21): 7013–25. 1992. doi:10.1128/jb.174.21.7013-7025.1992. PMID 1400251.
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