Biology:Human betaherpesvirus 6B
| Human betaherpesvirus 6B | |
|---|---|
Virus classification 
| |
| (unranked): | Virus |
| Realm: | Duplodnaviria |
| Kingdom: | Heunggongvirae |
| Phylum: | Peploviricota |
| Class: | Herviviricetes |
| Order: | Herpesvirales |
| Family: | Orthoherpesviridae |
| Genus: | Roseolovirus |
| Species: | Human betaherpesvirus 6B
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| Synonyms | |
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Human herpesvirus 6 | |
Human betaherpesvirus 6B (HHV-6B) is a species of virus in the genus Roseolovirus, subfamily Betaherpesvirinae, family Herpesviridae, and order Herpesvirales.[1]
Taxonomy
In 1992 the two variants were recognised within Human herpesvirus 6 on the basis of differing restriction endonuclease cleavages, monoclonal antibody reactions,[2] and growth patterns.[3] In 2012 these two variants were officially recognised as distinct species by the International Committee on Taxonomy of Viruses and named Human betaherpesvirus 6A and Human betaherpesvirus 6B.[4] Despite now being recognised as paraphyletic, the name Human herpesvirus 6 still sees usage in clinical contexts.
Pathology
Human betaherpesvirus 6B affects humans. Primary infection with this virus is the cause of the common childhood illness exanthema subitum (also known as roseola infantum or sixth disease). Additionally, reactivation is common in transplant recipients, which can cause several clinical manifestations such as encephalitis, bone marrow suppression, and pneumonitis.[5]
References
- ↑ "ICTV Master Species List 2018b.v2". https://talk.ictvonline.org/files/master-species-lists/m/msl/8266.[|permanent dead link|dead link}}]
- ↑ Kawabata, A.; Oyaizu, H.; Maeki, T.; Tang, H.; Yamanishi, K.; Mori, Y. (2011). "Analysis of a Neutralizing Antibody for Human Herpesvirus 6B Reveals a Role for Glycoprotein Q1 in Viral Entry". Journal of Virology 85 (24): 12962–71. doi:10.1128/JVI.05622-11. PMID 21957287.
- ↑ Braun, DK; Dominguez, G; Pellett, PE (1997). "Human herpesvirus 6". Clinical Microbiology Reviews 10 (3): 521–67. doi:10.1128/CMR.10.3.521. PMID 9227865.
- ↑ Adams, M. J.; Carstens, E. B. (2012). "Ratification vote on taxonomic proposals to the International Committee on Taxonomy of Viruses (2012)". Archives of Virology 157 (7): 1411–1422. doi:10.1007/s00705-012-1299-6. PMID 22481600.
- ↑ Yoshikawa, Tetsushi (2004). "Human herpesvirus 6 infection in hematopoietic stem cell transplant patients". British Journal of Haematology 124 (4): 421–32. doi:10.1046/j.1365-2141.2003.04788.x. PMID 14984492.
Colour indicates non-mammalian host: mollusc • frog • fish • bird • reptile –– Incertae sedis species listed below (sub)family –– Source: ICTV ––  Commons •  Wikispecies |
Wikidata ☰ Q24808741 entry
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