Biology:Methylornithine synthase

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Methylornithine synthase
Identifiers
EC number5.4.99.58
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

Methylornithine synthase (EC 5.4.99.58, PylB) is an enzyme with systematic name L-lysine carboxy-aminomethylmutase.[1][2] This enzyme catalyses the conversion of L-lysine into (3R)-3-methyl-D-ornithine.

The enzyme is a member of the superfamily of S-adenosyl-L-methionine-dependent radical enzymes.

References

  1. "The complete biosynthesis of the genetically encoded amino acid pyrrolysine from lysine". Nature 471 (7340): 647–50. March 2011. doi:10.1038/nature09918. PMID 21455182. Bibcode2011Natur.471..647G. 
  2. "Crystal structure of methylornithine synthase (PylB): insights into the pyrrolysine biosynthesis". Angewandte Chemie 51 (6): 1339–42. February 2012. doi:10.1002/anie.201106765. PMID 22095926. 

External links