Biology:N6-hydroxylysine O-acetyltransferase
From HandWiki
| N6-hydroxylysine O-acetyltransferase | |||||||||
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| Identifiers | |||||||||
| EC number | 2.3.1.102 | ||||||||
| CAS number | 101077-53-6 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a N6-hydroxylysine O-acetyltransferase (EC 2.3.1.102) is an enzyme that catalyzes the chemical reaction
- acetyl-CoA + N6-hydroxy-L-lysine [math]\displaystyle{ \rightleftharpoons }[/math] CoA + N6-acetyl-N6-hydroxy-L-lysine
Thus, the two substrates of this enzyme are acetyl-CoA and N6-hydroxy-L-lysine, whereas its two products are CoA and N6-acetyl-N6-hydroxy-L-lysine.
This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:N6-hydroxy-L-lysine 6-acetyltransferase. Other names in common use include N6-hydroxylysine:acetyl CoA N6-transacetylase, N6-hydroxylysine acetylase, and acetyl-CoA:6-N-hydroxy-L-lysine 6-acetyltransferase. This enzyme participates in lysine degradation.
References
- "Isolation and properties of N epsilon-hydroxylysine:acetyl coenzyme A N epsilon-transacetylase from Escherichia coli pABN11". Biochemistry 25 (9): 2485–9. 1986. doi:10.1021/bi00357a030. PMID 3521734.
- "Aerobactin biosynthesis and transport genes of plasmid ColV-K30 in Escherichia coli K-12". J. Bacteriol. 165 (2): 570–8. 1986. doi:10.1128/jb.165.2.570-578.1986. PMID 2935523.
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