Biology:Patchoulol synthase
From HandWiki
Short description: Class of enzymes
| Patchoulol synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 4.2.3.70 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Patchoulol synthase (EC 4.2.3.70) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (patchoulol-forming).[1][2][3] This enzyme catalyses the following chemical reaction
- (2E,6E)-farnesyl diphosphate + H2O [math]\displaystyle{ \rightleftharpoons }[/math] patchoulol + diphosphate
References
- ↑ "Biosynthesis of the sesquiterpene patchoulol from farnesyl pyrophosphate in leaf extracts of Pogostemon cablin (patchouli): mechanistic considerations". Archives of Biochemistry and Biophysics 256 (1): 56–68. July 1987. doi:10.1016/0003-9861(87)90425-5. PMID 3038029.
- ↑ "Purification and characterization of the sesquiterpene cyclase patchoulol synthase from Pogostemon cablin". Archives of Biochemistry and Biophysics 282 (1): 58–64. October 1990. doi:10.1016/0003-9861(90)90086-e. PMID 2171435.
- ↑ "Doubly deuterium-labeled patchouli alcohol from cyclization of singly labeled [2-2H1]farnesyl diphosphate catalyzed by recombinant patchoulol synthase". Journal of the American Chemical Society 132 (9): 2998–3008. March 2010. doi:10.1021/ja909251r. PMID 20148554.
External links
- Patchoulol+synthase at the US National Library of Medicine Medical Subject Headings (MeSH)
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