Biology:Pyrogallol hydroxytransferase
| Pyrogallol hydroxytransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 5.4.4.9 | ||||||||
| CAS number | 125978-84-9 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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Pyrogallol hydroxytransferase (EC 5.4.4.9) is an enzyme that catalyzes a chemical reaction that converts pyrogallol to phloroglucinol by formation of the intermediate 1,2,3,5-tetrahydroxybenzene.[1]
- REDIRECT Template:Chemical reaction
The enzyme isolated from the bacterium Pelobacter acidigallici contains molybdenum but the hydroxyl group which is initially added to pyrogallol does not come from water. Instead, some sulfoxides and aromatic N-oxides can provide these groups.[2][3]
Nomenclature
This enzyme belongs to the family of oxidoreductases. The systematic name of this enzyme class is 1,2,3,5-tetrahydroxybenzene:1,2,3-trihydroxybenzene hydroxytransferase. Other names in common use include 1,2,3,5-tetrahydroxybenzene hydroxyltransferase, 1,2,3,5-tetrahydroxybenzene:pyrogallol transhydroxylase, 1,2,3,5-tetrahydroxybenzene-pyrogallol hydroxyltransferase (transhydroxylase), pyrogallol hydroxyltransferase, 1,2,3,5-tetrahydroxybenzene:1,2,3-trihydroxybenzene hydroxyltransferase.[4]
References
- ↑ "Pyrogallol-to-phloroglucinol conversion and other hydroxyl-transfer reactions catalyzed by cell extracts of Pelobacter acidigallici". Journal of Bacteriology 172 (2): 1070–1076. February 1990. doi:10.1128/jb.172.2.1070-1076.1990. PMID 2298693.
- ↑ "Transhydroxylase of Pelobacter acidigallici: a molybdoenzyme catalyzing the conversion of pyrogallol to phloroglucinol". Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology 1204 (2): 217–224. February 1994. doi:10.1016/0167-4838(94)90011-6. PMID 8142462.
- ↑ "Towards the reaction mechanism of pyrogallol-phloroglucinol transhydroxylase of Pelobacter acidigallici". Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology 1430 (2): 245–253. March 1999. doi:10.1016/s0167-4838(99)00004-7. PMID 10082952. http://nbn-resolving.de/urn:nbn:de:bsz:352-opus-60102.
- ↑ Enzyme 5.4.4.9 at KEGG Pathway Database.
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