Biology:Thioethanolamine S-acetyltransferase

From HandWiki
thioethanolamine S-acetyltransferase
Identifiers
EC number2.3.1.11
CAS number9029-93-0
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

In enzymology, a thioethanolamine S-acetyltransferase (EC 2.3.1.11) is an enzyme that catalyzes the chemical reaction

acetyl-CoA + 2-aminoethanethiol ⇌ CoA + S-(2-aminoethyl)thioacetate

Thus, the two substrates of this enzyme are acetyl-CoA and 2-aminoethanethiol, whereas its two products are CoA and S-(2-aminoethyl)thioacetate.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:2-aminoethanethiol S-acetyltransferase. Other names in common use include thioltransacetylase B, thioethanolamine acetyltransferase, and acetyl-CoA:thioethanolamine S-acetyltransferase.

References

  • "Enzymatic thioltransacetylation". J. Biol. Chem. 211 (2): 621–9. 1954. PMID 13221570. 
  • McElroy, W.D. and Glass, B. (Eds.), A Symposium on the Mechanism of Enzyme Action, Johns Hopkins Press, Baltimore, 1954, p. 545-580.