Biology:Trehalose O-mycolyltransferase

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trehalose O-mycolyltransferase
Identifiers
EC number2.3.1.122
CAS number111694-11-2
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

In enzymology, a trehalose O-mycolyltransferase (EC 2.3.1.122) is an enzyme that catalyzes the chemical reaction

2 alpha,alpha-trehalose 6-mycolate [math]\displaystyle{ \rightleftharpoons }[/math] alpha,alpha-trehalose + alpha,alpha-trehalose 6,6'-bismycolate

Hence, this enzyme has one substrate( alpha,alpha'-trehalose 6-mycolate) and two products ( alpha,alpha-trehalose and alpha,alpha'-trehalose 6,6'-bismycolate).

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is alpha,alpha-trehalose-6-mycolate:alpha,alpha-trehalose-6-mycolate 6'-mycolyltransferase. Other names in common use include alpha,alpha'-trehalose 6-monomycolate:alpha,alpha'-trehalose, mycolyltransferase, alpha,alpha'-trehalose-6-mycolate:alpha,alpha'-trehalose-6-mycolate, and 6'-mycolyltransferase.

References

  • "Purification and characterization of a novel mycolic acid exchange enzyme from Mycobacterium smegmatis". J. Biol. Chem. 262 (28): 13417–23. 1987. PMID 3654621.