Chemistry:Co-tenidone
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Short description: Combination medication
| Combination of | |
|---|---|
| Atenolol | Beta blocker |
| Chlortalidone | Thiazide diuretic |
| Clinical data | |
| Routes of administration | Oral |
| Legal status | |
| Legal status |
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| Identifiers | |
| ChemSpider | |
| (verify) | |
Co-tenidone (BAN) is a non-proprietary name used to denote a combination of atenolol and chlortalidone. Co-tenidone is used in the treatment of hypertension. The use of β-blockers in hypertension was downgraded in June 2006 in the United Kingdom to fourth-line because they perform less well than other drugs, and because atenolol, the most frequently used β-blocker, at usual doses carries an unacceptable risk of provoking type 2 diabetes.[1]
Formulation
Two strengths of co-tenidone are currently available in the UK:
- 50 mg atenolol and 12.5 mg chlortalidone, BAN of Co-tenidone 50/12.5
- 100 mg atenolol and 25 mg chlortalidone, BAN of Co-tenidone 100/25
References
- British National Formulary 54, September 2007
Footnotes
- ↑ "NICE and BHS launch updated hypertension guideline". National Institute for Health and Clinical Excellence. 2006-06-28. https://www.nice.org.uk/guidance/cg34/resources/nice-and-the-british-hypertension-society-launch-updated-guideline-to-tackle-hypertension-in-england-and-wales-.
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