Chemistry:Tolonidine
From HandWiki
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| Preferred IUPAC name
N-(2-Chloro-4-methylphenyl)-4,5-dihydro-1H-imidazol-2-amine | |
| Identifiers | |
3D model (JSmol)
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PubChem CID
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| Properties | |
| C10H12ClN3 | |
| Molar mass | 209.67538 |
| Pharmacology | |
| 1=ATC code }} | C02AC04 (WHO) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
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Tracking categories (test):
Tolonidine is an antihypertensive.[1][2][3] It is an imidazoline receptor agonist, like moxonidine and rilmenidine.
See also
References
- ↑ Cosnier, D.; Duchene-Marullaz, P.; Grimal, J.; Rispat, G.; Streichenberger, G. (1975). "Pharmacological properties of 2-(2-chloro-p-toluidino)-2-imidazoline-nitrate (Tolonidine), a new antihypertensive agent. I. Action on blood pressure and heart rate". Arzneimittel-Forschung 25 (10): 1557–61. PMID 1243037.
- ↑ Cosnier, D.; Labrid, C.; Rispat, G.; Streichenberger, G. (1975). "Pharmacological properties of 2-(2-chloro-p-toluidino)-2-imidazoline-nitrate (tolonidine), a new antihypertensive agent. II. Action on cardiac contraction, circulatory parameters, autonomic receptors and diuresis". Arzneimittel-Forschung 25 (11): 1802–6. PMID 1243090.
- ↑ Cosnier, D.; Hache, J.; Labrid, C.; Streichenberger, G. (1975). "Pharmacological properties of 2-(2-chloro-p-toluidino)-2-imidazoline-nitrate (tolonidine), a new antihypertensive agent. III. Action on the secretions of the digestive tract and on the central nervous system, acute toxicity". Arzneimittel-Forschung 25 (12): 1926–33. PMID 3186.
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