Chemistry:Phenylpiracetam hydrazide

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Short description: Chemical compound
Phenylpiracetam hydrazide
Fonturacetam hydrazide.svg
Clinical data
Trade namesPhenylpiracetam hydrazide
Other namesFonturacetam hydrazide
Pregnancy
category
  • Unknown
Routes of
administration
Oral
ATC code
  • none
Legal status
Legal status
  • US: Not FDA approved; unscheduled
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC12H15N3O2
Molar mass233.271 g·mol−1
3D model (JSmol)
ChiralityRacemic mixture
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Phenylpiracetam hydrazide, also known as fonturacetam hydrazide,[1] is a racetam that is a derivative of phenylpiracetam in which the amide group is replaced with a hydrazide group. It was first reported by a Russian research group in 1980 as part of a series of chemical compounds investigated as anticonvulsants.[2] In an electroshock test it was found to have an ED50 of 310 mg/kg.[2]

Sale on the internet

All piracetam derivatives are not permitted to be sold as dietary supplements in the United States.[3] However, because they lack scheduling, piracetam derivatives like phenylpiracetam hydrazide are sold over the clear net accompanied by indications stating that the compound is "not for human consumption".[4]

See also

References

  1. "International Nonproprietary Names for Pharmaceutical Substances (INN). Recommended International Nonproprietary Names: List 63". WHO Drug Information 24 (1): 56. 2010. http://apps.who.int/medicinedocs/documents/s17753en/s17753en.pdf. Retrieved 26 November 2015. 
  2. 2.0 2.1 "Synthesis and anticonvulsive activity of 4-phenyl-2-pyrrolidinone-1-acetic acid amides" (in ru). Khimiko-Farmatsevticheskii Zhurnal 14 (11): 43–48. 1980. 
  3. "Presence of Piracetam in Cognitive Enhancement Dietary Supplements". JAMA Internal Medicine 180 (3): 458–459. March 2020. doi:10.1001/jamainternmed.2019.5507. PMID 31764936. 
  4. ""Not for human consumption": a review of emerging designer drugs". Pharmacotherapy 34 (7): 745–757. July 2014. doi:10.1002/phar.1424. PMID 24710806.