Chemistry:Suloctidil
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Short description: Chemical compound
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| Formula | C20H35NOS |
| Molar mass | 337.563 g·mol−1 |
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Suloctidil was a sulfur-containing aminoalcohol that was brought to market in the early 1970s as a vasodilator by Continental Pharma, a Belgian company.[1]:118–121[2][3]
Continental was bought by Monsanto in 1984, primarily on the promise of sales of suloctidil, which was approved in Europe at the time, but not in the US.[4] However, in 1985 Monsanto halted development and withdrew the drug worldwide following reports of liver toxicity.[5]:251
References
- ↑ Hladovec, Josef (1989). Antithrombotic Drugs in Thrombosis Models. CRC Press. ISBN 978-0-8493-5162-4.
- ↑ "Potential antilipolytic activity of suloctidil". Die Naturwissenschaften 62 (3): 141–2. March 1975. doi:10.1007/bf00623284. PMID 1240601. Bibcode: 1975NW.....62..141R.
- ↑ Buu-Hoi NP, Lambelin G, Roba J, Jacques G, Gillet C, "1-Subst-phenyl-2-amino-ethanols useful as beta adrenergic agents peripheral vasodilators and hypotensive agents", BE patent granted 739678
- ↑ "Monsanto's $150 mil. Life Sciences Research Center". 5 November 1984. https://www.pharmamedtechbi.com/publications/the-pink-sheet/46/045/monsantos-150-mil-life-sciences-research-center.
- ↑ "Consolidated List of Products Whose Consumption and/or Sale Have Been Banned, Withdrawn, Severely Restricted or not Approved by Governments Twelfth Issue: Pharmaceuticals". Department of Economic and Social Affairs of the United Nations Secretariat. New York: United Nations. 2005. https://www.un.org/esa/coordination/CL12.pdf.
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