Chemistry:Terizidone

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Short description: Chemical compound
Terizidone
Terizidone.svg
Clinical data
Other names4-[({4-[N-(3-oxo-1,2-oxazolidin-4-yl)carboximidoyl]phenyl}methylidene)amino]-1,2-oxazolidin-3-one
AHFS/Drugs.comInternational Drug Names
Pregnancy
category
  • C
ATC code
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
Chemical and physical data
FormulaC14H14N4O4
Molar mass302.290 g·mol−1
3D model (JSmol)
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Terizidone is a drug used in the treatment of tuberculosis.[1] Terizidone is mainly used in multi-drug-resistant tuberculosis (MDR-TB) in conjunction with other second-line drugs. It is a derivate of cycloserine and it is bacteriostatic.[2]

References

  1. "[Tolerability to terizidone (TZ) in the treatment of pulmonary tuberculosis in dialyzed patients]". Minerva Medica 82 (7–8): 477–81. 1991. PMID 1922892. 
  2. Rossiter, Dawn (2012). South African Medicines Formulary. Cape Town, South Africa: Health and Medical Publishing Group of the South African Medical Association. pp. 323–325. ISBN 978-1-875098-28-6.