Chemistry:Idrocilamide
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Short description: Muscle relaxant
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| Trade names | Talval, Srilane, Relaxnova, Brolitène |
| AHFS/Drugs.com | International Drug Names |
| Routes of administration | Topical |
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| Formula | C11H13NO2 |
| Molar mass | 191.230 g·mol−1 |
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Idrocilamide (trade names Talval, Srilane, Relaxnova, Brolitène[1]) is a medication with skeletal muscle relaxant[2] and anti-inflammatory actions[3] used as a topical cream to treat lumbago and other kinds of muscular pain;[4] it is available on prescription or over-the-counter[citation needed] in France and various other countries.[1]
Interactions
Idrocilamide has been reported to be a potent inhibitor of the metabolism of caffeine.[5][6]
References
- ↑ 1.0 1.1 Drugs.com: International Drug Names
- ↑ "The direct depressant effect of LCB29 (idrocilamide) on mechanical tension of rat soleus muscle fibers". Canadian Journal of Physiology and Pharmacology 68 (12): 1503–1509. 1990. doi:10.1139/y90-228. PMID 2085796.
- ↑ "[Tissue and systemic diffusion of idrocilamide after cutaneous administration]" (in French). Revue du Rhumatisme 60 (12): 932–6. 1993. PMID 8012322.
- ↑ "Clinical double-blind study with idrocilamide ointment in the treatment of acute lumbago". Acta Belgica. Medica Physica 13 (1): 29–32. 1990. PMID 2140002.
- ↑ "Clinically significant pharmacokinetic interactions between dietary caffeine and medications". Clinical Pharmacokinetics 39 (2): 127–53. 2000. doi:10.2165/00003088-200039020-00004. PMID 10976659.
- ↑ "Inhibition by idrocilamide of the disposition of caffeine". European Journal of Clinical Pharmacology 17 (1): 37–43. 1980. doi:10.1007/bf00561675. PMID 7371698.
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