Chemistry:Mofebutazone

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Short description: Chemical compound
Mofebutazone
Mofebutazone.svg
Clinical data
ATC code
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEBI
Chemical and physical data
FormulaC13H16N2O2
Molar mass232.283 g·mol−1
3D model (JSmol)
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Mofebutazone (or monophenylbutazone) is a drug used for joint and muscular pain.[1][2] It is a 3,5-pyrazolinedione derivative.

The drug binds to plasma albumin and competes with drugs such as coumarin anticoagulants, indomethacin and glucocorticoids.

References

  1. "Pharmacokinetics of [4-14C] mofebutazone after oral administration in man". European Journal of Drug Metabolism and Pharmacokinetics 9 (3): 223–227. 1984-07-01. doi:10.1007/BF03189645. PMID 6519123. 
  2. "Structure of phenylbutazone and mofebutazone in the crystalline state and in solution" (in English). Journal of Pharmaceutical Sciences 76 (12): 920–929. December 1987. doi:10.1002/jps.2600761217. PMID 3440938.