Chemistry:Fentiazac
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Short description: NSAID analgesic medication
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| Trade names | Norvedan |
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| Formula | C17H12ClNO2S |
| Molar mass | 329.80 g·mol−1 |
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| Melting point | 162–163 °C (324–325 °F) |
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Fentiazac is a thiazole-based nonsteroidal anti-inflammatory drug (NSAID) developed for use in joint and muscular pain.[1] Like most other NSAIDs, it acts through inhibition of prostaglandin synthesis, via non-selective inhibition of both COX-1 and COX-2. First described in 1974, it was synthesized using the Hantzsch thiazole synthesis.[2]
Fentiazac was marketed under the trade-name Norvedan (among others), but its market status is currently unknown and assumed to be discontinued.[3]
See also
References
- ↑ Nonsteroidal antiinflammatory drugs. 247. New York: Wiley. 1985. pp. 285. ISBN 978-0-471-89803-0.
- ↑ "Nonsteroidal antiinflammatory agents. 1.2,4-Diphenylthiazole-5-acetic acid and related compounds". Journal of Medicinal Chemistry 17 (11): 1177–1181. November 1974. doi:10.1021/jm00257a010. PMID 4414839.
- ↑ "FENTIAZAC" (in en). NCATS Inxight Drugs. National Center for Advancing Translational Sciences (NCATS); U.S. National Institutes of Health. https://drugs.ncats.io/substance/0YHF6E6NLS.
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