Chemistry:Nifenazone
From HandWiki
Nifenazone is a drug that has been used as an analgesic for a number of rheumatic conditions.[1]
Synthesis
Nifenazone is the amide formed when ampyrone and the acid chloride of nicotinic acid are combined in a Schotten–Baumann reaction.[2][3]
See also
- Aminopyrine
References
- ↑ "Trial of Nifenazone ("Thylin")". British Medical Journal 1 (5397): 1553–4. June 1964. doi:10.1136/bmj.1.5397.1553. PMID 14133613.
- ↑ "Über neue pharmakologisch wirksame Amide und Ester der Nicotinsäure". Monatshefte für Chemie 88 (3): 330–335. 1957. doi:10.1007/BF00901766.
- ↑ "Nifenazone". Pharmaceutical Substances. Georg Thieme Verlag KG. https://pharmaceutical-substances.thieme.com/ps/search-results?docUri=KD-14-0058.
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