Chemistry:Monoethanolamine oleate

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Short description: Pharmaceutical drug
Ethanolamine Oleate
Structural formula of monoethanolamine oleate.svg
Clinical data
AHFS/Drugs.comMultum Consumer Information
ATC code
Identifiers
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
Chemical and physical data
FormulaC20H41NO3
Molar mass343.552 g·mol−1
Density0.974 g/cm3
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Monoethanolamine oleate (ethanolammonium oleate) is an organic compound with the formula [CH3(CH2)7CH=CH(CH2)7CO2][H3NCH2CH2OH].. A colorless oily liquid, it is an example of a protic ionic liquid.[1] It is a salt formed by the reaction between monoethanolamine and oleic acid.[2]

Antivaricose agent

As an antivaricose agent, it is injected topically into varicosities to cause sclerosis (closure) of the abnormal vein. It is indicated for the treatment of patients with esophageal varices that have recently bled, to prevent rebleeding. Ethanolamine is not indicated for the treatment of patients with esophageal varices that have not bled. There is no evidence that treatment of this population decreases the likelihood of bleeding. Sclerotherapy with ethanolamine has no beneficial effect upon portal hypertension, the cause of esophageal varices, so that recanalization and collateralization may occur, necessitating reinjection.[3]

References

  1. "Phase Behavior and Physical Properties of New Biobased Ionic Liquid Crystals". The Journal of Physical Chemistry B 121 (14): 3177–3189. April 2017. doi:10.1021/acs.jpcb.7b01384. PMID 28332847. 
  2. "Synthesis and Thermophysical Properties of Two New Protic Long-Chain Ionic Liquids with the Oleate Anion". Fluid Phase Equilibria 299: 42–50. 2010. doi:10.1016/j.fluid.2010.08.022. 
  3. "Ethanolamine Oleate". https://www.rxlist.com/ethamolin-drug.htm.