Chemistry:Fluocinonide
From HandWiki
Short description: Chemical compound
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| Clinical data | |
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| Trade names | Fluonex, Lidex, others[1] |
| AHFS/Drugs.com | Micromedex Detailed Consumer Information |
| MedlinePlus | a601054 |
| Routes of administration | Topical |
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| Pharmacokinetic data | |
| Metabolism | Liver |
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| Chemical and physical data | |
| Formula | C26H32F2O7 |
| Molar mass | 494.532 g·mol−1 |
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Fluocinonide is a potent glucocorticoid used topically as an anti-inflammatory agent for the treatment of skin disorders such as eczema and seborrhoeic dermatitis.[2] It relieves itching, redness, dryness, crusting, scaling, inflammation, and discomfort.[2]
A common potential adverse effect is skin atrophy (thinning of the skin).[3]
In 2021, it was the 249th most commonly prescribed medication in the United States, with more than 1 million prescriptions.[4][5]
Veterinary uses
Fluocinonide is used in veterinary medicine. It is a treatment for allergies in dogs.[6] Natural systemic cortisol concentrations can be suppressed for weeks after one week of topical exposure.[7]
References
- ↑ "Fluocinonide Topical". MedlinePlus Drug Information. U.S. National Library of Medicine. https://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a601054.html.
- ↑ 2.0 2.1 "Fluocinonide Topical: MedlinePlus Drug Information" (in en). https://medlineplus.gov/druginfo/meds/a601054.html.
- ↑ "Comparative evaluation of skin atrophy in man induced by topical corticoids". The British Journal of Dermatology 100 (2): 193–206. February 1979. doi:10.1111/j.1365-2133.1979.tb05561.x. PMID 154921.
- ↑ "The Top 300 of 2021". https://clincalc.com/DrugStats/Top300Drugs.aspx.
- ↑ "Fluocinonide - Drug Usage Statistics". https://clincalc.com/DrugStats/Drugs/Fluocinonide.
- ↑ "Dog Allergies". Squidoo.
- ↑ "Adrenocortical suppression by topically applied corticosteroids in healthy dogs". Journal of the American Veterinary Medical Association 191 (6): 685–688. September 1987. PMID 2824410.
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