Chemistry:Troxerutin
From HandWiki
Short description: Chemical compound
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| Other names | Hydroxyethylrutoside (HER) Pherarutin Trihydroxyethylrutin 3',4',7-Tris[O-(2-hydroxyethyl)]rutin |
| AHFS/Drugs.com | International Drug Names |
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| Formula | C33H42O19 |
| Molar mass | 742.680 g·mol−1 |
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Troxerutin is a flavonol, a type of flavonoid, derived from rutin.[1] It is more accurately a hydroxyethylrutoside. It can be isolated from Sophora japonica, the Japanese pagoda tree.
It is used as a vasoprotective.[2]
Troxerutin has been shown in mice to reverse CNS insulin resistance and reduce reactive oxygen species induced by a high-cholesterol diet.[3]
References
- ↑ "Troxerutin improves hepatic lipid homeostasis by restoring NAD(+)-depletion-mediated dysfunction of lipin 1 signaling in high-fat diet-treated mice". Biochemical Pharmacology 91 (1): 74–86. September 2014. doi:10.1016/j.bcp.2014.07.002. PMID 25026599.
- ↑ "[Effectiveness of Troxerutin in association with Pycnogenol in the pharmacological treatment of venous insufficiency]". Minerva Cardioangiologica 52 (1): 43–8. February 2004. PMID 14765037.
- ↑ "Troxerutin protects against high cholesterol-induced cognitive deficits in mice". Brain 134 (Pt 3): 783–97. March 2011. doi:10.1093/brain/awq376. PMID 21252113.
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