Biology:Heme-transporting ATPase
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Short description: Class of enzymes
| heme-transporting ATPase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.6.3.41 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a heme-transporting ATPase (EC 3.6.3.41) is an enzyme that catalyzes the chemical reaction
- ATP + H2O + hemein [math]\displaystyle{ \rightleftharpoons }[/math] ADP + phosphate + hemeout
The 3 substrates of this enzyme are ATP, H2O, and heme, whereas its 3 products are ADP, phosphate, and heme.
This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides to catalyse transmembrane movement of substances. The systematic name of this enzyme class is ATP phosphohydrolase (heme-exporting). This enzyme participates in abc transporters - general.
References
- Saier MH Jr (1998). "Molecular phylogeny as a basis for the classification of transport proteins from bacteria, archaea and eukarya". Adv. Microb. Physiol.. Advances in Microbial Physiology 40: 81–136. doi:10.1016/S0065-2911(08)60130-7. ISBN 978-0-12-027740-7. PMID 9889977.
- "orf250 encodes a second subunit of an ABC-type heme transporter in Oenothera mitochondria". Mol. Gen. Genet. 246 (2): 166–73. 1995. doi:10.1007/BF00294679. PMID 7862087.
- "Discovery and sequence analysis of bacterial genes involved in the biogenesis of c-type cytochromes". J. Biol. Chem. 266 (12): 7793–803. 1991. PMID 1850420.
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