Biology:(R)-citramalate synthase
From HandWiki
Short description: Class of enzymes
| (R)-citramalate synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.3.1.182 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
(R)-citramalate synthase (EC 2.3.1.182, CimA) is an enzyme.[1][2] This enzyme catalyses the following chemical reaction
- acetyl-CoA + pyruvate + H2O [math]\displaystyle{ \rightleftharpoons }[/math] CoA + (2R)-2-hydroxy-2-methylbutanedioate
This enzyme participates in a novel pyruvate pathway for isoleucine biosynthesis.
References
- ↑ "(R)-citramalate synthase in methanogenic archaea". Journal of Bacteriology 181 (1): 331–3. January 1999. PMID 9864346.
- ↑ "Isoleucine biosynthesis in Leptospira interrogans serotype lai strain 56601 proceeds via a threonine-independent pathway". Journal of Bacteriology 186 (16): 5400–9. August 2004. doi:10.1128/jb.186.16.5400-5409.2004. PMID 15292141.
External links
- (R)-citramalate+synthase at the US National Library of Medicine Medical Subject Headings (MeSH)
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