Biology:TRD (gene)
From HandWiki
Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
T cell receptor delta locus (symbol TRD), also known as TCRD or TRD@, is a protein that in humans is encoded by the TRD gene.[1] It contributes the delta (δ) chain to the larger TCR protein (T-cell receptor).
References
Further reading
- "A new T-cell receptor gene located within the alpha locus and expressed early in T-cell differentiation". Nature 327 (6124): 677–82. 1987. doi:10.1038/327677a0. PMID 2439914. Bibcode: 1987Natur.327..677C.
- "An architectural perspective on signaling by the pre-, alphabeta and gammadelta T cell receptors". Immunological Reviews 191: 28–37. February 2003. doi:10.1034/j.1600-065X.2003.00011.x. PMID 12614349.
- "Use of a variable alpha region to create a functional T-cell receptor delta chain". Proceedings of the National Academy of Sciences of the United States of America 85 (15): 5634–8. August 1988. doi:10.1073/pnas.85.15.5634. PMID 2456576. Bibcode: 1988PNAS...85.5634G.
- "T-cell receptor delta-chain can substitute for alpha to form a beta delta heterodimer". Nature 340 (6234): 562–5. August 1989. doi:10.1038/340562a0. PMID 2528071. Bibcode: 1989Natur.340..562H.
- "T-cell receptor delta/alpha rearrangements in lymphoid neoplasms". Blood 74 (3): 1073–83. August 1989. doi:10.1182/blood.V74.3.1073.1073. PMID 2546634.
- "T cell receptor gamma and delta rearrangements in hematologic malignancies. Relationship to lymphoid differentiation". The Journal of Clinical Investigation 84 (2): 506–16. August 1989. doi:10.1172/JCI114193. PMID 2547833.
- "Identification and sequence of a fourth human T cell antigen receptor chain". Nature 330 (6148): 569–72. 1988. doi:10.1038/330569a0. PMID 2825032.
- "Molecular diversity of gammadelta T cells in peripheral blood from patients with B-cell chronic lymphocytic leukaemia". Neoplasma 49 (2): 86–90. 2002. PMID 12088111.
- "Preferential expansion of Vgamma9-JgammaP/Vdelta2-Jdelta3 gammadelta T cells in nasal T-cell lymphoma and chronic active Epstein-Barr virus infection". The American Journal of Pathology 162 (5): 1629–38. May 2003. doi:10.1016/S0002-9440(10)64297-6. PMID 12707047.
- "Cutting edge: TCR delta gene is frequently rearranged in adult B lymphocytes". Journal of Immunology 171 (2): 524–7. July 2003. doi:10.4049/jimmunol.171.2.524. PMID 12847212.
- T-γδ Receptor Restriction in Peripheral Lymphocytes of Patients with Behçet's Disease. Advances in Experimental Medicine and Biology. 528. 2003. pp. 267–8. doi:10.1007/0-306-48382-3_53. ISBN 0-306-47757-2.
- "Vdelta2-Jalpha rearrangements are frequent in precursor-B-acute lymphoblastic leukemia but rare in normal lymphoid cells". Blood 103 (10): 3798–804. May 2004. doi:10.1182/blood-2003-08-2952. PMID 14656882.
- "Ontogeny of gamma delta T cells in humans". Journal of Immunology 172 (3): 1637–45. February 2004. doi:10.4049/jimmunol.172.3.1637. PMID 14734745.
- "Lymphoid differentiation pathways can be traced by TCR delta rearrangements". Journal of Immunology 175 (4): 2495–500. August 2005. doi:10.4049/jimmunol.175.4.2495. PMID 16081821.
- "T-cell receptor repertoire of circulating gamma delta T-cells in Takayasu's arteritis". Clinical Immunology 118 (2–3): 243–9. 2006. doi:10.1016/j.clim.2005.10.010. PMID 16307908.
- "Human alpha beta and gamma delta thymocyte development: TCR gene rearrangements, intracellular TCR beta expression, and gamma delta developmental potential--differences between men and mice". Journal of Immunology 176 (3): 1543–52. February 2006. doi:10.4049/jimmunol.176.3.1543. PMID 16424183.
- "Deregulation of cyclin D2 by juxtaposition with T-cell receptor alpha/delta locus in t(12;14)(p13;q11)-positive childhood T-cell acute lymphoblastic leukemia". European Journal of Haematology 77 (1): 27–34. July 2006. doi:10.1111/j.0902-4441.2006.t01-1-EJH2553.x. PMID 16548914.
- "Gene-specific signal joint modifications during V(D)J recombination of TCRAD locus genes in murine and human thymocytes". Immunobiology 211 (9): 741–51. 2006. doi:10.1016/j.imbio.2006.04.001. PMID 17015149. http://www.hal.inserm.fr/inserm-00079238.
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