Biology:TRNAMet cytidine acetyltransferase
From HandWiki
TRNAMet cytidine acetyltransferase | |||||||||
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Identifiers | |||||||||
EC number | 2.3.1.193 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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TRNAMet cytidine acetyltransferase (EC 2.3.1.193, YpfI, TmcA) is an enzyme with systematic name acetyl-CoA:(elongator tRNAMet)-cytidine34 N4-acetyltransferase (ATP-hydrolysing).[1][2] This enzyme catalyses the following chemical reaction
- [elongator tRNAMet]-cytidine34 + ATP + acetyl-CoA [math]\displaystyle{ \rightleftharpoons }[/math] CoA + [elongator tRNAMet]-N4-acetylcytidine34 + ADP + phosphate
The enzyme acetylates the wobble base C34 of the CAU anticodon of elongation-specific tRNAMet.
References
- ↑ "The RNA acetyltransferase driven by ATP hydrolysis synthesizes N4-acetylcytidine of tRNA anticodon". The EMBO Journal 27 (16): 2194–203. August 2008. doi:10.1038/emboj.2008.154. PMID 18668122.
- ↑ "RNA helicase module in an acetyltransferase that modifies a specific tRNA anticodon". The EMBO Journal 28 (9): 1362–73. May 2009. doi:10.1038/emboj.2009.69. PMID 19322199.
External links
- TRNAMet+cytidine+acetyltransferase at the US National Library of Medicine Medical Subject Headings (MeSH)
Original source: https://en.wikipedia.org/wiki/TRNAMet cytidine acetyltransferase.
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