Biology:CDP-glycerol diphosphatase
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Short description: Class of enzymes
| CDP-glycerol diphosphatase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.6.1.16 | ||||||||
| CAS number | 37289-28-4 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a CDP-glycerol diphosphatase (EC 3.6.1.16) is an enzyme that catalyzes the chemical reaction
- CDP-glycerol + H2O [math]\displaystyle{ \rightleftharpoons }[/math] CMP + sn-glycerol 3-phosphate
Thus, the two substrates of this enzyme are CDP-glycerol and H2O, whereas its two products are CMP and sn-glycerol 3-phosphate.
This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides in phosphorus-containing anhydrides. The systematic name of this enzyme class is CDP-glycerol phosphoglycerohydrolase. Other names in common use include CDP-glycerol pyrophosphatase, and cytidine diphosphoglycerol pyrophosphatase. This enzyme participates in glycerophospholipid metabolism.
References
- "The synthesis of teichoic acid IV. On the regulation of cytidine 5′-diphosphateglycerol concentration". Biochimica et Biophysica Acta (BBA) - Mucoproteins and Mucopolysaccharides 101: 6–15. March 1965. doi:10.1016/0926-6534(65)90025-4. PMID 14329291.
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