Biology:Sorbose 5-dehydrogenase (NADP+)
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sorbose 5-dehydrogenase (NADP+) | |||||||||
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Identifiers | |||||||||
EC number | 1.1.1.123 | ||||||||
CAS number | 37250-52-5 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a sorbose 5-dehydrogenase (NADP+) (EC 1.1.1.123) is an enzyme that catalyzes the chemical reaction
- L-sorbose + NADP+ [math]\displaystyle{ \rightleftharpoons }[/math] 5-dehydro-D-fructose + NADPH + H+
Thus, the two substrates of this enzyme are L-sorbose and NADP+, whereas its 3 products are 5-dehydro-D-fructose, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is L-sorbose:NADP+ 5-oxidoreductase. Other names in common use include 5-ketofructose reductase, 5-keto-D-fructose reductase, sorbose (nicotinamide adenine dinucleotide phosphate) dehydrogenase, reduced nicotinamide adenine dinucleotide phosphate-linked, reductase, and sorbose 5-dehydrogenase (NADP+).
References
- "5-keto-D-fructose. VI. A specific reduced nicotinamide adenine dinucleotide phosphate-linked reductase from yeast". J. Biol. Chem. 245 (6): 1311–8. 1970. PMID 4392628.
![]() | Original source: https://en.wikipedia.org/wiki/Sorbose 5-dehydrogenase (NADP+).
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