Biology:Mannitol dehydrogenase (cytochrome)
From HandWiki
| mannitol dehydrogenase (cytochrome) | |||||||||
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| Identifiers | |||||||||
| EC number | 1.1.2.2 | ||||||||
| CAS number | 37250-78-5 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a mannitol dehydrogenase (cytochrome) (EC 1.1.2.2) is an enzyme that catalyzes the chemical reaction
- D-mannitol + ferricytochrome c [math]\displaystyle{ \rightleftharpoons }[/math] D-fructose + ferrocytochrome c
Thus, the two substrates of this enzyme are D-mannitol and ferricytochrome c, whereas its two products are D-fructose and ferrocytochrome c.
This enzyme belongs to the family of oxidoreductases, to be specific those acting on the CH-OH group of donor with a cytochrome as acceptor. The systematic name of this enzyme class is D-mannitol:ferricytochrome-c 2-oxidoreductase. This enzyme is also called polyol dehydrogenase. This enzyme participates in pentose and glucuronate interconversions and fructose and mannose metabolism
References
- "Polyol dehydrogenases. 2. The polyol dehydrogenases of Acetobacter suboxydans and Candida utilis". Biochem. J. 64 (3): 385–94. 1956. PMID 13373782.
- "Purification and characterization of polyol dehydrogenase from Gluconobacter melanogenus". Han'guk Saenghwa Hakhaochi 23: 172–178. 1990.
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