Biology:Decaprenylphospho-beta-D-ribofuranose 2-oxidase
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Decaprenylphospho-beta-D-ribofuranose 2-oxidase | |||||||||
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Identifiers | |||||||||
EC number | 1.1.98.3 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Decaprenylphospho-beta-D-ribofuranose 2-oxidase (EC 1.1.98.3, decaprenylphosphoryl-beta-D-ribofuranose 2'-epimerase, Rv3790, DprE1) is an enzyme with systematic name trans,octacis-decaprenylphospho-beta-D-ribofuranose:FAD 2-oxidoreductase.[1][2] This enzyme catalyses the following chemical reaction
- trans,octacis-decaprenylphospho-beta-D-ribofuranose + FAD [math]\displaystyle{ \rightleftharpoons }[/math] trans,octacis-decaprenylphospho-beta-D-erythro-pentofuranosid-2-ulose + FADH2
This enzyme from the bacterium Mycobacterium smegmatis participates in epimerization of trans,octacis-decaprenylphospho-beta-D-ribofuranose to trans,octacis-decaprenylphospho-beta-D-arabinoofuranose.
References
- ↑ "Analogous mechanisms of resistance to benzothiazinones and dinitrobenzamides in Mycobacterium smegmatis". PLOS ONE 6 (11): e26675. 2011. doi:10.1371/journal.pone.0026675. PMID 22069462. Bibcode: 2011PLoSO...626675D.
- ↑ "Benzothiazinones are suicide inhibitors of mycobacterial decaprenylphosphoryl-β-D-ribofuranose 2'-oxidase DprE1". Journal of the American Chemical Society 134 (2): 912–5. January 2012. doi:10.1021/ja211042r. PMID 22188377. http://infoscience.epfl.ch/record/174323.
External links
- Decaprenylphospho-beta-D-ribofuranose+2-oxidase at the US National Library of Medicine Medical Subject Headings (MeSH)
![]() | Original source: https://en.wikipedia.org/wiki/Decaprenylphospho-beta-D-ribofuranose 2-oxidase.
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