Biology:Tartrate dehydrogenase
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tartrate dehydrogenase | |||||||||
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![]() Tartrate dehydrogenase tetramer, Pseudomonas putida | |||||||||
Identifiers | |||||||||
EC number | 1.1.1.93 | ||||||||
CAS number | 37250-29-6 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a tartrate dehydrogenase (EC 1.1.1.93) is an enzyme that catalyzes the chemical reaction
- tartrate + NAD+ [math]\displaystyle{ \rightleftharpoons }[/math] oxaloglycolate + NADH + H+
Thus, the two substrates of this enzyme are tartrate and NAD+, whereas its 3 products are oxaloglycolate, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is tartrate:NAD+ oxidoreductase. This enzyme is also called mesotartrate dehydrogenase. This enzyme participates in glyoxylate and dicarboxylate metabolism. It employs one cofactor, manganese.
References
- "Tartaric acid metabolism. V. Crystalline tartrate dehydrogenase". J. Biol. Chem. 243 (10): 2479–85. 1968. PMID 4297261.
![]() | Original source: https://en.wikipedia.org/wiki/Tartrate dehydrogenase.
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