Biology:Steroid-transporting ATPase
From HandWiki
| Steroid-transporting ATPase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.6.3.45 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Steroid-transporting ATPase (EC 3.6.3.45, pleiotropic-drug-resistance protein, PDR protein) is an enzyme with systematic name ATP phosphohydrolase (steroid-exporting).[1][2][3] This enzyme catalyses the following chemical reaction
- ATP + H2O + steroidin [math]\displaystyle{ \rightleftharpoons }[/math] ADP + phosphate + steroidout
This enzyme has two similar ATP-binding domains.
References
- ↑ "Molecular cloning and characterization of a novel gene of Candida albicans, CDR1, conferring multiple resistance to drugs and antifungals". Current Genetics 27 (4): 320–9. March 1995. doi:10.1007/BF00352101. PMID 7614555.
- ↑ "bfr1+, a novel gene of Schizosaccharomyces pombe which confers brefeldin A resistance, is structurally related to the ATP-binding cassette superfamily". Journal of Bacteriology 177 (6): 1536–43. March 1995. PMID 7883711.
- ↑ "The ATP binding cassette transporters Pdr5 and Snq2 of Saccharomyces cerevisiae can mediate transport of steroids in vivo". The Journal of Biological Chemistry 271 (41): 25167–72. October 1996. doi:10.1074/jbc.271.41.25167. PMID 8810273.
External links
- Steroid-transporting+ATPase at the US National Library of Medicine Medical Subject Headings (MeSH)
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