Biology:N-acylmannosamine 1-dehydrogenase

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N-acylmannosamine 1-dehydrogenase
Identifiers
EC number1.1.1.233
CAS number117698-08-5
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

In enzymology, a N-acylmannosamine 1-dehydrogenase (EC 1.1.1.233) is an enzyme that catalyzes the chemical reaction

N-acyl-D-mannosamine + NAD+ [math]\displaystyle{ \rightleftharpoons }[/math] N-acyl-D-mannosaminolactone + NADH + H+

Thus, the two substrates of this enzyme are N-acyl-D-mannosamine and NAD+, whereas its 3 products are N-acyl-D-mannosaminolactone, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is N-acyl-D-mannosamine:NAD+ 1-oxidoreductase. Other names in common use include N-acylmannosamine dehydrogenase, N-acetyl-D-mannosamine dehydrogenase, N-acyl-D-mannosamine dehydrogenase, and N-acylmannosamine dehydrogenase.

References

  • "Purification and properties of N-acyl-D-mannosamine dehydrogenase from Flavobacterium sp. 141-8". J. Biochem. (Tokyo) 104 (3): 466–71. September 1988. PMID 3240988.