Biology:Unspecific peroxygenase
From HandWiki
Short description: Class of enzymes
| Unspecific peroxygenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 1.11.2.1 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Unspecific peroxygenase (EC 1.11.2.1, aromatic peroxygenase, mushroom peroxygenase, haloperoxidase-peroxygenase, Agrocybe aegerita peroxidase) is an enzyme with systematic name substrate:hydrogen peroxide oxidoreductase (RH-hydroxylating or -epoxidising).[1][2][3][4][5][6][7][8][9] This enzyme catalyses the following chemical reaction
- RH + H2O2 [math]\displaystyle{ \rightleftharpoons }[/math] ROH + H2O
Unspecific peroxygenase is a heme-thiolate protein comparable to Cytochrome P450 in the ability to catalyze a variety of P450 reactions (hence "unspecific"), but forms a unique, solely fungal, protein family of extracellular enzymes.
References
- ↑ "Novel haloperoxidase from the agaric basidiomycete Agrocybe aegerita oxidizes aryl alcohols and aldehydes". Applied and Environmental Microbiology 70 (8): 4575–81. August 2004. doi:10.1128/AEM.70.8.4575-4581.2004. PMID 15294788.
- ↑ "The haloperoxidase of the agaric fungus Agrocybe aegerita hydroxylates toluene and naphthalene". FEBS Letters 579 (27): 6247–50. November 2005. doi:10.1016/j.febslet.2005.10.014. PMID 16253244.
- ↑ "The coprophilous mushroom Coprinus radians secretes a haloperoxidase that catalyzes aromatic peroxygenation". Applied and Environmental Microbiology 73 (17): 5477–85. September 2007. doi:10.1128/AEM.00026-07. PMID 17601809.
- ↑ "Pyridine as novel substrate for regioselective oxygenation with aromatic peroxygenase from Agrocybe aegerita". FEBS Letters 582 (29): 4100–6. December 2008. doi:10.1016/j.febslet.2008.11.006. PMID 19022254.
- ↑ "Conversion of dibenzothiophene by the mushrooms Agrocybe aegerita and Coprinellus radians and their extracellular peroxygenases". Applied Microbiology and Biotechnology 82 (6): 1057–66. April 2009. doi:10.1007/s00253-008-1778-6. PMID 19039585.
- ↑ "Regioselective preparation of 5-hydroxypropranolol and 4'-hydroxydiclofenac with a fungal peroxygenase". Bioorganic & Medicinal Chemistry Letters 19 (11): 3085–7. June 2009. doi:10.1016/j.bmcl.2009.04.015. PMID 19394224. https://naldc-legacy.nal.usda.gov/naldc/download.xhtml?id=39462&content=PDF.
- ↑ "Hydroxylation of naphthalene by aromatic peroxygenase from Agrocybe aegerita proceeds via oxygen transfer from H2O2 and intermediary epoxidation". Applied Microbiology and Biotechnology 81 (6): 1071–6. January 2009. doi:10.1007/s00253-008-1704-y. PMID 18815784. https://boris.unibe.ch/31603/.
- ↑ "Oxidative cleavage of diverse ethers by an extracellular fungal peroxygenase". The Journal of Biological Chemistry 284 (43): 29343–9. October 2009. doi:10.1074/jbc.M109.040857. PMID 19713216.
- ↑ "Molecular characterization of aromatic peroxygenase from Agrocybe aegerita". Applied Microbiology and Biotechnology 84 (5): 885–97. October 2009. doi:10.1007/s00253-009-2000-1. PMID 19434406. https://boris.unibe.ch/31601/.
External links
 |  |
